ArticleCell stem cell2019
Restricted Hematopoietic Progenitors and Erythropoiesis Require SCF from Leptin Receptor+ Niche Cells in the Bone Marrow.
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Article in Cell stem cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers.
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0cells of the map it votes in
121citing papers in PubMed
16.5field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
121 citing papers in PubMed, 184 citations in OpenAlex.
- Endothelial PERK restricts lymphoid regeneration by reducing DLL4-NOTCH3 signaling at the Pre-B niche.Cell reports · 2026Article
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- Vascular-lymphatic dual circulation in bone health and disease: Mechanistic coupling and translational therapeutics.Journal of orthopaedic translation · 2026Review
- From bud to stem: dynamics of hematopoietic stem cells that drive homing and mobilization.Current opinion in hematology · 2026Review
- LepR+ Fibroblasts in Maladaptive Cardiac Fibrosis: Mechanisms and Controversies.Circulation research · 2026Article
- Blood Pharming of Red Cells.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2026Review
- Acquired nonpermissive BM microenvironment impairs HSC proliferation and maintenance, and B-cell development after HSCT.Blood advances · 2026Article
- Osteocyte-derived erythroferrone regulates liver hepcidin during stress erythropoiesis.Blood advances · 2026Article
- Post-translational Modifications in Proteins: Prediction Methods, Biological Functions, and Diseases.MedComm · 2026Review
- Metabolic and epigenetic interplay in HSPC specification: A balance between extrinsic and intrinsic cues.iScience · 2026Review
- The bone marrow microenvironment during homeostasis and after myeloablation.Journal of bone and mineral metabolism · 2026Review
- A single cell atlas defines perinatal factors that drive murine bone marrow development.bioRxiv : the preprint server for biology · 2026Article
- Hematopoietic organoids: Opportunities and challenges in modeling human hematopoiesis and diseases in vitro.Stem cell reports · 2026Review
- Conventional and Alternative B Lymphopoiesis: Multiple Roads to Immunity.Stem cell reviews and reports · 2026Review
- An inflammatory T-cell-stromal axis contributes to hematopoietic stem/progenitor cell failure and clonal evolution in human myelodysplastic syndrome.Nature communications · 2025Article
- Inflammatory pathways and the bone marrow microenvironment in inherited bone marrow failure syndromes.Stem cells (Dayton, Ohio) · 2025Review
- Nonselective β-Adrenergic Receptor Inhibitors Impair Hematopoietic Regeneration in Mice and Humans after Hematopoietic Cell Transplants.Cancer discovery · 2025Article
- Periarteriolar niches become inflamed in aging bone marrow, remodeling the stromal microenvironment and depleting lymphoid progenitors.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Skeletal stem and progenitor cells in bone physiology, ageing and disease.Nature reviews. Endocrinology · 2025Review
- Endothelial heterogeneity in bone marrow: insights across development, adult life and leukemia.Leukemia · 2025Review
61 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Stefano ComazzettoChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Malea M MurphyChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Stefano BertoDepartment of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Elise JefferyChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Zhiyu ZhaoChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Sean J MorrisonChildren's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: sean.morrison@utsouthwestern.edu.
The University of Texas Southwestern Medical Center · USHoward Hughes Medical Institute · US
Funding
The Regulation of Stem Cell AgingR37AG024945 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI MORRISON, SEAN J · 2009 to 2018
$3.1MGenetic analysis of stem cell maintenance in vivoR01HL097760 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI MORRISON, SEAN J · 2009 to 2012
$1.5MThe Regulation of Stem Cell AgingR01AG024945 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MORRISON, SEAN J · 2004 to 2008
$1.1MLaser Scanning Confocal for UT Southwestern Live Cell Imaging FacilityS10OD021684 · OD · UT SOUTHWESTERN MEDICAL CENTER · PI LUBY-PHELPS, KATHERINE J · 2016 to 2016
$455kNeural regulation of the hematopoietic stem cell nicheF32HL124947 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI MURPHY, MALEA M · 2014 to 2017
$157kHoward Hughes Medical InstituteNHLBI NIH HHS F32 HL124947NHLBI NIH HHS R01 HL097760NIA NIH HHS R01 AG024945NIA NIH HHS R37 AG024945NIH HHS S10 OD021684
Abstract
Hematopoietic stem cells (HSCs) are maintained in a perivascular niche in bone marrow, in which leptin receptor
Indexed as
ErythropoiesisStem Cell NicheAnimalsBone MarrowCells, CulturedEndothelial CellsHematopoietic Stem CellsLymphoid Progenitor CellsMiceMice, TransgenicMyeloid Progenitor CellsReceptors, LeptinStem Cell FactorLEPR protein, humanReceptors, LeptinStem Cell Factorendothelial cellserythropoiesisleptin receptor(+) stromal cellsnicherestricted hematopoietic progenitorssinusoidstem cell factor
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.