Evidence map›Paper›PMID 30661931›Full record

ArticleCell metabolism2019

Activation of Anxiogenic Circuits Instigates Resistance to Diet-Induced Obesity via Increased Energy Expenditure.

Xiangyang Xie, Haili Yang, Juan Ji An, Jessica Houtz, Ji-Wei Tan, Haifei Xu, Guey-Ying Liao, Zhi-Xiang Xu, Baoji Xu

Open access · bronzeAbstract read
In one paragraph

Article in Cell metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Xiangyang XieDepartment of Neuroscience, The Scripps Research Institute Florida, Jupiter, FL 33458, USA.
Haili YangDepartment of Neuroscience, The Scripps Research Institute Florida, Jupiter, FL 33458, USA.
Juan Ji AnDepartment of Neuroscience, The Scripps Research Institute Florida, Jupiter, FL 33458, USA.
Jessica HoutzDepartment of Neuroscience, The Scripps Research Institute Florida, Jupiter, FL 33458, USA.
Ji-Wei TanDepartment of Neuroscience, The Scripps Research Institute Florida, Jupiter, FL 33458, USA.
Haifei XuDepartment of Neuroscience, The Scripps Research Institute Florida, Jupiter, FL 33458, USA.
Guey-Ying LiaoDepartment of Neuroscience, The Scripps Research Institute Florida, Jupiter, FL 33458, USA.
Zhi-Xiang XuDepartment of Neuroscience, The Scripps Research Institute Florida, Jupiter, FL 33458, USA.
Baoji XuDepartment of Neuroscience, The Scripps Research Institute Florida, Jupiter, FL 33458, USA. Electronic address: bxu@scripps.edu.
Scripps Research Institute · US

Funding

CENTER FOR NEUROANATOMY WITH NEUROTROPIC VIRUSES: COMPARATIVE MEDICINEP40RR018604 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI STRICK, PETER · 2004 to 2011
$6.5M
TrkB Neurons in the Control of Body WeightR01DK105954 · NIDDK · UNIVERSITY OF FLORIDA · PI XU, BAOJI · 2016 to 2022
$4.6M
Unraveling the Role of PVH BDNF Neurons in Energy BalanceR01DK103335 · NIDDK · UNIVERSITY OF FLORIDA · PI XU, BAOJI · 2015 to 2022
$4.4M
Investigating the role of TrkB neurons in thermoregulationF32NS106810 · NINDS · SCRIPPS FLORIDA · PI HOUTZ, JESSICA · 2018 to 2019
$106k
NCRR NIH HHS P40 RR018604NIDDK NIH HHS R01 DK103335NIDDK NIH HHS R01 DK105954NINDS NIH HHS F32 NS106810
6 · The paper itself

Abstract

Anxiety disorders are associated with body weight changes in humans. However, the mechanisms underlying anxiety-induced weight changes remain poorly understood. Using Emx1

Indexed as

Adipose TissueAnimalsAnti-Anxiety AgentsBody WeightBromazepamCarbolinesDietEnergy MetabolismMiceMice, Inbred StrainsObesityAnti-Anxiety Agentsbeta-carboline-3-carboxylic acid N-methylamideBromazepamCarbolinesadaptive thermogenesisamygdalaanxietyanxiogenic circuitsbasal metabolic ratebrain-derived neurotrophic factorcortexhyperthermialeannessresistance to diet-induced obesity

Identifiers

PMID30661931
PMCPMC6507421
OpenAlexW2909747915

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.