Evidence map›Paper›PMID 30661479›Full record

ArticleHypertension (Dallas, Tex. : 1979)2019

Pregnancy Increases Ca

Xiang-Qun Hu, Rui Song, Monica Romero, Chiranjib Dasgupta, Xiaohui Huang, Mark A Holguin, VaShon Williams, Daliao Xiao, Sean M Wilson, Lubo Zhang

Open access · bronzeAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Guidelines for assessing maternal cardiovascular physiology during pregnancy and postpartum.American journal of physiology. Heart and circulatory physiology · 2024
    Guideline
  2. Review
  3. The uteroplacental circulation at high altitude: adaptation and maladaptation.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review
  4. Article
  5. Placental Adaptation to Hypoxia: The Case of High-Altitude Pregnancies.International journal of environmental research and public health · 2025
    Review
  6. Rad-mediated inhibition of CaThe Journal of physiology · 2024
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. CaInternational journal of molecular sciences · 2023
    Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Long-Term Hypoxia Negatively Influences CaFrontiers in physiology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Xiang-Qun HuFrom the Lawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University School of Medicine, CA.
Rui SongFrom the Lawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University School of Medicine, CA.
Monica RomeroFrom the Lawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University School of Medicine, CA.
Chiranjib DasguptaFrom the Lawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University School of Medicine, CA.
Xiaohui HuangFrom the Lawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University School of Medicine, CA.
Mark A HolguinFrom the Lawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University School of Medicine, CA.
VaShon WilliamsFrom the Lawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University School of Medicine, CA.
Daliao XiaoFrom the Lawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University School of Medicine, CA.
Sean M WilsonFrom the Lawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University School of Medicine, CA.
Lubo ZhangFrom the Lawrence D. Longo, MD Center for Perinatal Biology, Department of Basic Sciences, Loma Linda University School of Medicine, CA.
Loma Linda University · US

Funding

Uterine Vascular Adaptation to Pregnancy and Chronic HypoxiaP01HD083132 · NICHD · LOMA LINDA UNIVERSITY · PI DUCSAY, CHARLES A · 2016 to 2020
$6.3M
Epigenetic mechanisms of uterine vascular adaptation to pregnancy and hypoxiaR01HL128209 · NHLBI · LOMA LINDA UNIVERSITY · PI ZHANG, LUBO · 2015 to 2018
$1.6M
Uterine Arterial Spontaneous Transient Outward Currents in PregnancyR01HL137649 · NHLBI · LOMA LINDA UNIVERSITY · PI ZHANG, LUBO · 2017 to 2020
$1.6M
NHLBI NIH HHS R01 HL128209NHLBI NIH HHS R01 HL137649NICHD NIH HHS P01 HD083132
6 · The paper itself

Abstract

Spontaneous transient outward currents (STOCs) at physiological membrane potentials of vascular smooth muscle cells fundamentally regulate vascular myogenic tone and blood flow in an organ. We hypothesize that heightened STOCs play a key role in uterine vascular adaptation to pregnancy. Uterine arteries were isolated from nonpregnant and near-term pregnant sheep. Ca

Indexed as

Pregnancy, AnimalAdaptation, PhysiologicalAnimalsCalciumFemaleMembrane PotentialsMicroscopy, ConfocalModels, AnimalMuscle, Smooth, VascularPatch-Clamp TechniquesPregnancyRegional Blood FlowSheepUterine ArteryUterusVasoconstrictionCalciumestrogenpregnancyprogesteroneryanodineuterine artery

Identifiers

PMID30661479
PMCPMC6374197
OpenAlexW2915043132

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.