ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2019
The impact of cancer type, treatment, and distress on health-related quality of life: cross-sectional findings from a study of Australian cancer patients.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- The prevalence of anxiety symptoms/disorders in cancer patients: a meta-analysis.Frontiers in psychiatry · 2024Pooled it
- Factors associated with psychological distress among newly diagnosed patients with gastric cancer: A cross-sectional study.Asia-Pacific journal of oncology nursing · 2026Article
- Factors associated with health-related quality of life in survivors of childhood-onset and adult-onset cancer compared to controls.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Quality of Life After Microvascular Alveolar Ridge Reconstruction with Subsequent Dental Rehabilitation.Journal of clinical medicine · 2024Article
- Incidence and risk factors for psychological distress in adult female patients with breast cancer: a systematic review and meta-analysis.Frontiers in psychiatry · 2024Review
- Understanding the pathways linking patient-centered communication to cancer survivors' emotional health: examining the mediating roles of self-efficacy and cognitive reappraisal.Journal of cancer survivorship : research and practice · 2023Article
- Risk Factors of Health-Related Quality of Life among Gastrointestinal Cancer Survivors in the U.S.: With a Focus on Social and Behavioral Determinants of Health (SBDH).International journal of environmental research and public health · 2023Article
- Role of sex on psychological distress, quality of life, and coping of patients with advanced colorectal and non-colorectal cancer.World journal of gastrointestinal oncology · 2022Article
- Managing uncertainty and responding to difficult emotions: Cancer patients' perspectives on clinician response during the COVID-19 pandemic.Patient education and counseling · 2022Article
- Gender Differences in Psychological Distress in Patients with Colorectal Cancer and Its Correlates in the Northeast of Iran.Journal of gastrointestinal cancer · 2022Article
- Health-related quality of life in advanced colorectal cancer patients in China: a nationwide hospital-based survey.Annals of translational medicine · 2022Article
- Cannabinoids pharmacological effects are beyond the palliative effects: CB2 cannabinoid receptor agonist induced cytotoxicity and apoptosis in human colorectal cancer cells (HT-29).Molecular and cellular biochemistry · 2021Article
- The effect of the type of surgery performed due to prostate cancer on preoperative patient anxiety, a prospective study.American journal of clinical and experimental urology · 2021Article
- Organizing Psycho-Oncological Care for Cancer Patients: The Patient's Perspective.Frontiers in psychology · 2021Article
- Article
- Severe symptoms and very low quality-of-life among outpatients newly diagnosed with advanced cancer: data from a multicenter cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Article
- Cutaneous adverse events and quality of life in outpatients receiving anticancer agents: results from an observational, cross-sectional study.Drugs in context · 2020Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study examined the mediating effects of cancer type, treatment, and distress on health-related quality of life (HRQoL) for early diagnosis cancer patients. Results were interpreted with respect to established thresholds for clinical meaningfulness.
methodsA cross-sectional design was used. Patients completed surveys collecting demographics, cancer type, treatment, comorbid conditions, distress (HADS), and HRQoL (FACT-G). Hierarchical multivariate regressions examined associations between cancer type, treatment, and distress on HRQoL. Established minimum differences were used to identify clinically meaningful changes in HRQoL.
resultsOf the 1183 patients surveyed, 21% were classified as having elevated anxiety and 13% had elevated depression. Our sample reported significantly lower physical and emotional well-being compared to population norms. Patients with prostate, melanoma, gynaecological, and urological cancers had higher HRQoL scores than those with colorectal cancer. However, when effects for treatment type and distress were considered, differences between cancer types became non-significant. Anxiety and depression were associated with lower HRQoL scores as was chemotherapy. Only depression, anxiety, and chemotherapy were associated with clinically meaningful decreases in HRQoL scores.
conclusionsWhile statistically significant differences in HRQoL were found between different cancer types, only chemotherapy, anxiety, and depression produced clinically meaningful poorer HRQoL scores. In practice, clinically meaningful differences could promote a shift in resources toward interventions where a positive effect on patient well-being is appreciated by both the patient and health professional.
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