Evidence map›Paper›PMID 30661174›Full record

ArticleIrish journal of medical science2019

Food-dependent exercise-induced reactions: lessons from a 15-year retrospective study.

Aisling Farrell, Ciaran Judge, Vyanka Redenbaugh, Hanna Awad, Niall Conlon

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Article in Irish journal of medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Aisling FarrellDepartment of Immunology, St. James's Hospital, Dublin, Ireland. aisling.farrell@ucdconnect.ie.ORCID http://orcid.org/0000-0003-1949-3792
Ciaran JudgeDepartment of Immunology, St. James's Hospital, Dublin, Ireland.
Vyanka RedenbaughDepartment of Immunology, St. James's Hospital, Dublin, Ireland.
Hanna AwadDepartment of Immunology, St. James's Hospital, Dublin, Ireland.
Niall ConlonDepartment of Immunology, St. James's Hospital, Dublin, Ireland.
St. James's Hospital · IETrinity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFood-dependent exercise-induced anaphylaxis (FDEIA) is a life-threatening disorder in which the signs and symptoms of anaphylaxis occur if physical exertion occurs within a few hours of exposure to a food.

aimsThe aim of this study was to characterise patients diagnosed with FDEIA and related disorders.

methodsA retrospective review of electronic clinical data from 2001 to 2016 was carried out. Fifty-seven cases were identified and analysed to establish clinical features, triggering factors and sensitisation patterns.

resultsThe number of patients per annum diagnosed with FDEIA or related reactions increased from 1 in 2001 to 18 patients in 2016. Sixty-nine percent reported systemic symptoms consistent with anaphylaxis, and 31% had skin manifestations only. In 33% of cases, the level of triggering exercise was mild. Forty-four percent of patients were sensitised to the omega-5-gliadin fraction of wheat.

conclusionsFDEIA is an increasingly recognised serious allergic disease. The clinical diagnosis is supported by targeted sensitisation testing and molecular-based allergy diagnostics. These tools allow implementation of effective dietary and lifestyle modifications that mitigate against future serious reactions. Given the limited access to physicians with specialist allergy training in Ireland, increased awareness of this condition amongst sports medicine specialists and general physicians is required.

Indexed as

AdolescentAdultAnaphylaxisExerciseFemaleFood HypersensitivityHumansMaleMiddle AgedRetrospective StudiesTime FactorsYoung AdultAllergyAnaphylaxisExercise-induced anaphylaxisFood allergyFood-dependent exercise-induced anaphylaxis

Identifiers

PMID30661174
OpenAlexW2908534359

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.