ReviewCurrent psychiatry reports2019
A Review of the Relationship Between Emotional Learning and Memory, Sleep, and PTSD.
Review in Current psychiatry reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 105 citations in OpenAlex.
- Sleep efficiency predicts improvements in fear extinction and PTSD symptoms during prolonged exposure for veterans with comorbid insomnia.Psychiatry research · 2023Trial
- Sleep impairments in refugees diagnosed with post-traumatic stress disorder: a polysomnographic and self-report study.European journal of psychotraumatology · 2023Trial
- Early risk factors and six month posttraumatic stress disorder symptom severity following trauma.European journal of psychotraumatology · 2026Article
- Shorter sleep duration predicts altered next-day physiologic, behavioral, and corticolimbic responses during fear extinction recall in youth.Neurobiology of learning and memory · 2026Article
- Efficacy of imagery rehearsal therapy in the treatment of traumatic nightmares in youth with complex post-traumatic stress disorder.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Review
- Association of Sleep Quality, Sleep Disturbances, and Chronotype with Post-Traumatic Stress Disorder in Earthquake-Exposed Adolescents.Children (Basel, Switzerland) · 2026Article
- Fear of Sleep in the Acute Aftermath of Trauma Predicts Future Posttraumatic Stress Disorder: The Moderating Role of Community Violence Exposure.Behavioral sciences (Basel, Switzerland) · 2026Article
- The impact of trauma and how to intervene: a narrative review of psychotraumatology over the past 15 years.European journal of psychotraumatology · 2025Article
- The Association Between Adverse Childhood Experiences and Sleep in Children with Autism Spectrum Disorder.Journal of autism and developmental disorders · 2025Article
- Mild Traumatic Brain Injury Impairs Fear Extinction and Network Excitability in the Infralimbic Cortex.Journal of neurotrauma · 2025Article
- Review
- Biomarker Correlations in PTSD: IL-18, IRE1, pERK, and ATF6 via Courtauld Emotional Control Scale (CECS).International journal of molecular sciences · 2025Article
- The value of multimodal neuroimaging in the diagnosis and treatment of post-traumatic stress disorder: a narrative review.Translational psychiatry · 2025Review
- Article
- Insomnia and Mental Health Outcomes After Catastrophic Disasters: A Cross-Sectional Study Examining the Long-Term Effects of the Beirut Port Explosion.Neuropsychiatric disease and treatment · 2025Article
- Post traumatic stress and sleep disorders in long COVID: Patient management and treatment.Life sciences · 2024Review
- Targeted memory reactivation with sleep disruption does not weaken week-old memories.NPJ science of learning · 2024Article
- The role of objective sleep in implicit and explicit affect regulation: A comprehensive review.Neurobiology of stress · 2024Article
- Infralimbic activity during REM sleep facilitates fear extinction memory.Current biology : CB · 2024Article
- REM disruption and REM Vagal Activity Predict Extinction Recall in Trauma-Exposed Individuals.bioRxiv : the preprint server for biology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
purpose of reviewThe emotional memory and learning model of PTSD posits maladaptive fear conditioning, extinction learning, extinction recall, and safety learning as central mechanisms to PTSD. There is increasingly convincing support that sleep disturbance plays a mechanistic role in these processes. The current review consolidates the evidence on the relationships between emotional memory and learning, disturbed sleep, and PTSD acquisition, maintenance, and treatment. RECENT
findingsWhile disrupted sleep prior to trauma predicts PTSD onset, maladaptive fear acquisition does not seem to be the mechanism through which PTSD is acquired. Rather, poor extinction learning/recall and safety learning seem to better account for who maintains acute stress responses from trauma versus who naturally recovers; there is convincing evidence that this process is, at least in part, mediated by REM fragmentation. Individuals with PTSD had higher "fear load" during extinction, worse extinction learning, poorer extinction recall, and worse safety learning. Evidence suggests that these processes are also mediated by fragmented REM. Finally, PTSD treatments that require extinction and safety learning may also be affected by REM fragmentation. Addressing fragmented sleep or sleep architecture could be used to increase emotional memory and learning processes and thus ameliorate responses to trauma exposure, reduce PTSD severity, and improve treatment. Future studies should examine relationships between emotional memory and learning and disturbed sleep in clinical PTSD patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.