ArticleiScience2019
Exercise Training Induces Depot-Specific Adaptations to White and Brown Adipose Tissue.
Article in iScience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed.
- No evidence of brown adipose tissue activation after 24 weeks of supervised exercise training in young sedentary adults in the ACTIBATE randomized controlled trial.Nature communications · 2022Trial
- Tissue-Specific Angiogenic Responses to Exercise: Mechanisms and Research Advances.Biomolecules · 2026Review
- Exercise and Fat: A Primer.Sports medicine - open · 2026Review
- Obesity and Exercise: New Insights and Perspectives.Endocrine reviews · 2025Review
- The protective role of brown adipose tissue in cardiac cell damage after myocardial infarction and heart failure.Lipids in health and disease · 2024Review
- The Effects of Obesity, Six Weeks of Aerobic Training, and Cold Water Exposure on the Expression of FNDC5 and UCP1 Genes in Male Wistar Rats.International journal of endocrinology and metabolism · 2024Article
- Exercise as a tool to mitigate metabolic disease.American journal of physiology. Cell physiology · 2024Review
- The characterization of metabolic changes in adipose tissues and muscles due to different exercise intensities by Dixon in healthy young men.European journal of radiology · 2024Article
- Effects of swimming in cold water on lipolysis indicators via fibroblast growth factor-21 in male Wistar rats.Biochemistry and biophysics reports · 2024Article
- The Role of Exerkines in Obesity-Induced Disruption of Mitochondrial Homeostasis in Thermogenic Fat.Metabolites · 2024Review
- Review
- Transplantation of committed pre-adipocytes from brown adipose tissue improves whole-body glucose homeostasis.iScience · 2024Article
- White adipose tissue mitochondrial bioenergetics in metabolic diseases.Reviews in endocrine & metabolic disorders · 2023Review
- High-throughput proteomics uncovers exercise training and type 2 diabetes-induced changes in human white adipose tissue.Science advances · 2023Article
- Development and expansion of intramuscular adipose tissue is not dependent on UCP-1-lineage cells in mice.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2023Article
- Exercise-induced regulation of adipose tissue.Current opinion in genetics & development · 2023Review
- Brown adipose tissue and aging: A potential role for exercise.Experimental gerontology · 2023Review
- The Sympathetic Innervation of Adipose Tissues: Regulation, Functions, and Plasticity.Comprehensive Physiology · 2023Article
- Eccentric and concentric exercises induce different adaptions in adipose tissue biology.Journal of physiology and biochemistry · 2023Article
- Differential remodeling of subcutaneous white and interscapular brown adipose tissue by long-term exercise training in aged obese female mice.Journal of physiology and biochemistry · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
Exercise affects whole-body metabolism through adaptations to various tissues, including adipose tissue (AT). Recent studies investigated exercise-induced adaptations to AT, focusing on inguinal white adipose tissue (WAT), perigonadal WAT, and interscapular brown adipose tissue (iBAT). Although these AT depots play important roles in metabolism, they account for only ∼50% of the AT mass in a mouse. Here, we investigated the effects of 3 weeks of exercise training on all 14 AT depots. Exercise induced depot-specific effects in genes involved in mitochondrial activity, glucose metabolism, and fatty acid uptake and oxidation in each adipose tissue (AT) depot. These data demonstrate that exercise training results in unique responses in each AT depot; identifying the depot-specific adaptations to AT in response to exercise is essential to determine how AT contributes to the overall beneficial effect of exercise.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.