Evidence map›Paper›PMID 30660722›Full record

Trial reportOsteoarthritis and cartilage2019

Sagittal plane walking biomechanics in individuals with knee osteoarthritis after quadriceps strengthening.

H C Davis, B A Luc-Harkey, M K Seeley, J Troy Blackburn, B Pietrosimone

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Osteoarthritis and cartilage, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Step-by-step insight into gait analysis: A narrative review unlocking knee biomechanics.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026
    Review
  4. Article
  5. Elastic Shape Analysis of Movement Data.Journal of the American Statistical Association · 2025
    Article
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  11. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

H C DavisUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: davishc@live.unc.edu.
B A Luc-HarkeyBrigham and Women's Hospital, Boston, MA, USA. Electronic address: bharkey@bwh.harvard.edu.
M K SeeleyBrigham Young University, Provo, UT, USA. Electronic address: matthewkseeley@gmail.com.
J Troy BlackburnUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: troyb@email.unc.edu.
B PietrosimoneUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: brian@unc.edu.

Funding

Improving Disability in Knee Osteoarthritis by Targeting Neuromuscular DeficitsR21AR067560 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PIETROSIMONE, BRIAN · 2015 to 2016
$368k
NIAMS NIH HHS R21 AR067560
6 · The paper itself

Abstract

objectiveTo compare sagittal walking gait biomechanics between participants with knee osteoarthritis (KOA) who increased quadriceps strength following a lower-extremity strengthening intervention (responders) and those who did not increase strength following the same strengthening protocol (non-responders) both at baseline and following the lower extremity strengthening protocol.

designFifty-three participants with radiographic KOA (47% female, 62.3 ± 7.1 years, BMI = 28.5 ± 3.9 kg/m

resultsA significant group x time interaction for KFA demonstrated greater KFA in the first half of stance at baseline and greater knee extension in the second half of stance at 4-weeks in responders compared to non-responders. There was no significant group x time interaction for vGRF or internal KEM.

conclusionsQuadriceps strengthening may be used to stimulate small changes in KFA in individuals with KOA.

Indexed as

AdultAgedBiomechanical PhenomenaDisability EvaluationFemaleGaitHumansKnee JointMaleMiddle AgedMuscle StrengthOsteoarthritis, KneePain MeasurementQuadriceps MuscleRange of Motion, ArticularResistance TrainingFunctional data analysisInternal knee extension momentKnee flexion angleVertical ground reaction forceWaveform analysis

Identifiers

PMID30660722
PMCPMC6475608

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.