Trial reportOsteoarthritis and cartilage2019
Model-based pain and function outcome trajectory types for patients undergoing knee arthroplasty: a secondary analysis from a randomized clinical trial.
Trial report in Osteoarthritis and cartilage, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.
- Are preoperative psychological factors associated with chronic postoperative pain after total knee arthroplasty: a systematic review.EFORT open reviews · 2026Pooled it
- Perioperative Opioid Use and Dosage Trajectories Vary Depending on Pain Outcome Classification and Bodily Pain in Patients who Catastrophize About Their Pain: A Secondary Analysis of a Randomized Trial in Knee Arthroplasty.The journal of pain · 2024Trial
- Phase 3 Trials of Enhanced Versus Usual Care Physical Therapy for Patients at Risk of Poor Outcome Following Knee Arthroplasty: A Perspective on Meaning and a Way Forward.Physical therapy · 2021Trial
- Physical Therapy Use, Costs, and Value for Latent Classes of Good vs Poor Outcome in Patients Who Catastrophize About Their Pain Prior to Knee Arthroplasty.Archives of physical medicine and rehabilitation · 2021Trial
- Racial Differences in Pain and Function Following Knee Arthroplasty: A Secondary Analysis From a Multicenter Randomized Clinical Trial.Arthritis care & research · 2021Trial
- Response to Letter: Analytic approaches for prognostic studies of persistent pain following knee arthroplasty.Acta orthopaedica · 2026Article
- Letter to the Editor: Analytic approaches for prognostic studies of persistent pain following knee arthroplasty.Acta orthopaedica · 2026Article
- The Impact of Human Placental Tissue-Derived Xenograft on Bone Healing and Pain Behaviors in a Murine Segmental Bone Defect Model.Military medicine · 2026Article
- Trajectories of Work Ability After Total Hip and Knee Arthroplasty: A Latent Class Growth Analysis.Journal of occupational rehabilitation · 2026Article
- Investigating the dynamic relationship between joint function outcomes and kinesiophobia following total knee arthroplasty.Frontiers in psychology · 2026Article
- Inflammatory phenotypes after total knee arthroplasty: a testable framework for biomarker-stratified enhanced recovery and precision rehabilitation.Frontiers in medicine · 2026Article
- Sociodemographic Differences in Long-Term Function After Total Hip and Knee Arthroplasty: A Scoping Review.Orthopaedic surgery · 2025Article
- Article
- The efficacy of an interdisciplinary pain management program for complex regional pain syndrome compared to low back pain and chronic widespread pain: an observational study.Pain medicine (Malden, Mass.) · 2025Observational
- Chronic postsurgical pain and transitional pain services: a narrative review highlighting European perspectives.Regional anesthesia and pain medicine · 2025Review
- Examination of nonlinear longitudinal processes with latent variables, latent processes, latent changes, and latent classes in the structural equation modeling framework: The R package nlpsem.Behavior research methods · 2025Article
- Quantitative Analysis of the Minimum Clinically Important Difference in the Brief Pain Inventory After Total Knee Arthroplasty.Journal of pain research · 2025Article
- siRNAs, tRNAs, and rRNAs in Osteoarthritis: Biological Functions and Therapeutic Opportunities.Biologics : targets & therapy · 2025Review
- Head-to-head comparison of appropriate use criteria for knee arthroplasty: A multicenter cohort study.Osteoarthritis and cartilage open · 2024Article
- Using Two Predictive Models to Capture Two Types of Poor Outcomes in Knee Arthroplasty: A Multisite Longitudinal Cohort Study.Arthritis & rheumatology (Hoboken, N.J.) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 6 institutions in 1 country.
Funding
Abstract
objectiveKnee arthroplasty (KA) is an effective surgical procedure. However, clinical studies suggest that a considerable number of patients continue to experience substantial pain and functional loss following surgical recovery. We aimed to estimate pain and function outcome trajectory types for persons undergoing KA, and to determine the relationship between pain and function trajectory types, and pre-surgery predictors of trajectory types.
designParticipants were 384 patients who took part in the KA Skills Training randomized clinical trial. Pain and function were assessed at 2-week pre- and 2-, 6-, and 12-months post-surgery. Piecewise latent class growth models were used to estimate pain and function trajectories. Pre-surgery variables were used to predict trajectory types.
resultsThere was strong evidence for two trajectory types, labeled as good and poor, for both Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain and Function scores. Model estimated rates of the poor trajectory type were 18% for pain and function. Dumenci's latent kappa between pain and function trajectory types was 0.71 (95% CI: 0.61-0.80). Pain catastrophizing and number of painful body regions were significant predictors of poor pain and function outcomes. Outcome-specific predictors included low income for poor pain and baseline pain and younger age for poor function.
conclusionsAmong adults undergoing KA, approximately one-fifth continue to have persistent pain, poor function, or both. Although the poor pain and function trajectory types tend to go together within persons, a significant number experience either poor pain or function but not both, suggesting heterogeneity among persons who do not fully benefit from KA.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.