Evidence map›Paper›PMID 30660639›Full record

ArticleThe Journal of allergy and clinical immunology2019

Hypoxia enhances CD8

Fangkun Ning, Katsuyuki Takeda, Michaela Schedel, Joanne Domenico, Anthony Joetham, Erwin W Gelfand

Open access · greenAbstract read
In one paragraph

Article in The Journal of allergy and clinical immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Type 2 immunity in allergic diseases.Cellular & molecular immunology · 2025
    Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. T-cell responses in asthma exacerbations.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022
    Review
  10. Article
  11. Article
  12. Possible selection bias limits the interpretation of single-cell transcriptomics data of steroid-resistant asthma exacerbation.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  13. Review
  14. Review
  15. CD8European respiratory review : an official journal of the European Respiratory Society · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Fangkun NingDivision of Cell Biology, Department of Pediatrics, National Jewish Health, Denver, Colo.
Katsuyuki TakedaDivision of Cell Biology, Department of Pediatrics, National Jewish Health, Denver, Colo.
Michaela SchedelDivision of Cell Biology, Department of Pediatrics, National Jewish Health, Denver, Colo.
Joanne DomenicoDivision of Cell Biology, Department of Pediatrics, National Jewish Health, Denver, Colo.
Anthony JoethamDivision of Cell Biology, Department of Pediatrics, National Jewish Health, Denver, Colo.
Erwin W GelfandDivision of Cell Biology, Department of Pediatrics, National Jewish Health, Denver, Colo. Electronic address: erwin3460@gmail.com.
National Jewish Health · USUniversity of Colorado Denver · US

Funding

Signaling Memory in Chronic AsthmaP01HL036577 · NHLBI · NATIONAL JEWISH HEALTH · PI GELFAND, ERWIN WILLIAM · 1986 to 2011
$18.7M
Naturally Occurring T Regulatory Cells Control Airway HyperresponsivenessR01AI077609 · NIAID · NATIONAL JEWISH HEALTH · PI GELFAND, ERWIN WILLIAM · 2009 to 2013
$2.3M
Naturally occurring T regulatory cells control airway hyperresponsivenessR56AI077609 · NIAID · NATIONAL JEWISH HEALTH · PI GELFAND, ERWIN WILLIAM · 2008 to 2008
$487k
NHLBI NIH HHS P01 HL036577NIAID NIH HHS R01 AI077609NIAID NIH HHS R56 AI077609
6 · The paper itself

Abstract

backgroundCD8

objectiveWe determined the effects of hypoxia exposure on IL-13-producing CD8

methodsCD8

resultsUnder hypoxic conditioning, CD8

conclusionsHypoxia enhances CD8

Indexed as

AnimalsBasic Helix-Loop-Helix ProteinsBronchoconstrictor AgentsCD8-Positive T-LymphocytesCells, CulturedEndothelial PAS Domain-Containing Protein 1HypoxiaHypoxia-Inducible Factor 1, alpha SubunitInflammationLungMethacholine ChlorideMice, TransgenicRespiratory HypersensitivityBasic Helix-Loop-Helix ProteinsBronchoconstrictor AgentsEndothelial PAS Domain-Containing Protein 1Hif1a protein, mouseHypoxia-Inducible Factor 1, alpha SubunitMethacholine ChlorideAsthmaCD8(+) T cellshypoxiahypoxia-inducible factor 1αIL-13

Identifiers

PMID30660639
PMCPMC11098440
OpenAlexW2911056238

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.