ArticleCell systems2019
Global Topological Order Emerges through Local Mechanical Control of Cell Divisions in the Arabidopsis Shoot Apical Meristem.
Article in Cell systems, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A multiscale growth atlas of Arabidopsis: linking cell dynamics to organ development.The New phytologist · 2026Pooled it
- Inferring cell division from cell shape.The Plant cell · 2026Article
- Quantification of cell-type-specific plasmodesmata distribution in Arabidopsis roots reveals spatial and patterning dynamics.The Plant journal : for cell and molecular biology · 2026Article
- Spatial variation in the mutation rate within the plant shoot apical meristem.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Topological analysis of 3D digital ovules identifies cellular patterns associated with ovule shape diversity.Development (Cambridge, England) · 2024Article
- Large-volume fully automated cell reconstruction generates a cell atlas of plant tissues.The Plant cell · 2024Article
- A somatic genetic clock for clonal species.Nature ecology & evolution · 2024Article
- Mechanics of reproductive differentiation in the land plants: a paradigm shift?Frontiers in plant science · 2024Article
- Tissues as networks of cells: towards generative rules of complex organ development.Journal of the Royal Society, Interface · 2023Review
- Whole-mount smFISH allows combining RNA and protein quantification at cellular and subcellular resolution.Nature plants · 2023Article
- Role of turgor-pressure induced boundary tension in the maintenance of the shoot apical meristem ofJournal of the Royal Society, Interface · 2023Article
- Composition, structure and robustness of Lichen guilds.Scientific reports · 2023Article
- Topological properties accurately predict cell division events and organization of shoot apical meristem in Arabidopsis thaliana.Development (Cambridge, England) · 2022Article
- The annotation and analysis of complex 3D plant organs using 3DCoordX.Plant physiology · 2022Article
- Combined computational modeling and experimental analysis integrating chemical and mechanical signals suggests possible mechanism of shoot meristem maintenance.PLoS computational biology · 2022Article
- Using positional information to provide context for biological image analysis with MorphoGraphX 2.0.eLife · 2022Article
- Microtubule-based perception of mechanical conflicts controls plant organ morphogenesis.Science advances · 2022Article
- X-ray microscopy enables multiscale high-resolution 3D imaging of plant cells, tissues, and organs.Plant physiology · 2022Article
- Embodiment in distributed information processing: "Solid" plants versus "liquid" ant colonies.Quantitative plant biology · 2022Review
- Testing candidate genes linked to corolla shape variation of a pollinator shift in Rhytidophyllum (Gesneriaceae).PloS one · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
The control of cell position and division act in concert to dictate multicellular organization in tissues and organs. How these processes shape global order and molecular movement across organs is an outstanding problem in biology. Using live 3D imaging and computational analyses, we extracted networks capturing cellular connectivity dynamics across the Arabidopsis shoot apical meristem (SAM) and topologically analyzed the local and global properties of cellular architecture. Locally generated cell division rules lead to the emergence of global tissue-scale organization of the SAM, facilitating robust global communication. Cells that lie upon more shorter paths have an increased propensity to divide, with division plane placement acting to limit the number of shortest paths their daughter cells lie upon. Cell shape heterogeneity and global cellular organization requires KATANIN, providing a multiscale link between cell geometry, mechanical cell-cell interactions, and global tissue order.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.