Evidence map›Paper›PMID 30660549›Full record

ArticleJACC. Cardiovascular imaging2019

Radiomic Analysis of Myocardial Native T

Ulf Neisius, Hossam El-Rewaidy, Shiro Nakamori, Jennifer Rodriguez, Warren J Manning, Reza Nezafat

Abstract readComparative Study
In one paragraph

Article in JACC. Cardiovascular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
114citing papers in PubMed, 6 pooled it
16.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

114 citing papers in PubMed, 6 syntheses or guidelines pooled it, 187 citations in OpenAlex.

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54 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ulf NeisiusDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Hossam El-RewaidyDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Shiro NakamoriDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Jennifer RodriguezDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Warren J ManningDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts; Department of Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
Reza NezafatDepartment of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts. Electronic address: rnezafat@bidmc.harvard.edu.
Beth Israel Deaconess Medical Center · US

Funding

Cardiovascular MRI Characterization of the Arrhythmogenic Heart in Nonischemic CardiomyopathyR01HL129185 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI NEZAFAT, REZA · 2015 to 2024
$6.4M
Imaging Markers of Subclinical Cardiotoxicity in Breast CancerR01HL127015 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI NEZAFAT, REZA · 2016 to 2020
$3.5M
Myocardial Tissue Characterization with MR Relaxometry in Heart FailureR01HL129157 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI NEZAFAT, REZA · 2017 to 2020
$3.2M
MRI Characterization of Arrhythmogenic Scar in Ventricular TachycardiaR21HL127650 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ANTER, ELAD, NEZAFAT, REZA · 2015 to 2016
$479k
NHLBI NIH HHS R01 HL127015NHLBI NIH HHS R01 HL129157NHLBI NIH HHS R01 HL129185NHLBI NIH HHS R21 HL127650
6 · The paper itself

Abstract

objectivesThis study sought to examine the diagnostic ability of radiomic texture analysis (TA) on quantitative cardiovascular magnetic resonance images to differentiate between hypertensive heart disease (HHD) and hypertrophic cardiomyopathy (HCM).

backgroundHHD and HCM are associated with increased left ventricular wall thickness (LVWT). Contemporary guidelines define HCM as LVWT ≥15 mm that is unexplained by other disease, which complicates diagnosis in cases of co-occurrences. Conventional global native T

methodsThis study identified 232 subjects (53 with HHD, 108 with HCM, and 71 control subjects) for TA who consecutively underwent free-breathing multislice native T

resultsThe selected texture features provided the maximum diagnostic accuracy of 86.2% (c-statistic: 0.820; 95% confidence interval [CI]: 0.769 to 0.903) using the SVM. For the test validation dataset, the accuracy of the pattern remained high at 80.0% (c-statistic: 0.89; 95% CI: 0.77 to 1.00). Global native T

conclusionsRadiomics analysis of native T

Indexed as

Image Interpretation, Computer-AssistedMagnetic Resonance ImagingAdultAgedCardiomyopathy, HypertrophicCase-Control StudiesDiagnosis, DifferentialFemaleFibrosisHumansHypertensionHypertrophy, Left VentricularMaleMiddle AgedPredictive Value of TestsProof of Concept Studycardiovascular magnetic resonancehypertensive heart diseasehypertrophic cardiomyopathyleft ventricular hypertrophyradiomicsT(1) mapping

Identifiers

PMID30660549
PMCPMC7032053
OpenAlexW2909339748

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.