ReviewReproductive biology and endocrinology : RB&E2019
"Bisphenol a: an emerging threat to male fertility".
Review in Reproductive biology and endocrinology : RB&E, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 2 syntheses or guidelines pooled it, 160 citations in OpenAlex.
- Renin-Angiotensin System Role in Cardiovascular Effects of Plasticizers: A Systematic Review.Cardiovascular toxicology · 2025Pooled it
- Endocrine disruption rewards: bisphenol-A-induced reproductive toxicity and the precision ameliorative potential of flavonoids in preclinical studies. A systematic review and meta-analysis.Frontiers in toxicology · 2025Pooled it
- The impact of animal models on translating male infertility research from bench to bedside: a narrative review.Reproductive biology and endocrinology : RB&E · 2026Review
- Germ cell risk assessment of combined exposure to monosodium glutamate and bisphenol A in male SD rat: deciphering the molecular mechanisms.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- Protective Effects ofAntioxidants (Basel, Switzerland) · 2026Article
- Transgenerational reproductive risks of BPA: epigenetic mechanisms and biomarker applications. A critical review.Environmental epigenetics · 2026Review
- The influence of environmental and chemical exposures on fertility in the Eastern Mediterranean region: A narrative review.International journal of reproductive biomedicine · 2025Review
- Article
- Therapeutic Effects of Naringin on Bisphenol A-Induced Oxidative Stress Damage in Nervous and Reproductive Systems of Cockerel Chickens.Veterinary medicine and science · 2025Article
- Lifestyle and Environmental Factors Affecting Male Fertility, Individual Predisposition, Prevention, and Intervention.International journal of molecular sciences · 2025Review
- Effects of bisphenol A, bisphenol S, and tetramethyl bisphenol F on male fertility inToxicology and industrial health · 2025Article
- A comprehensive review on potential role of selenium, selenoproteins and selenium nanoparticles in male fertility.Heliyon · 2024Review
- The Olfactory Receptor Olfr25 Mediates Sperm Dysfunction Induced by Low-Dose Bisphenol A through the CatSper-CaToxics · 2024Article
- Metabolomics reveals that ferroptosis participates in bisphenol A-induced testicular injury.Heliyon · 2024Article
- The Association of ICSI Outcomes with Semen and Blood Bisphenol A Concentrations of the Male Partner.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Decrease in Sperm Parameters in the 21st Century: Obesity, Lifestyle, or Environmental Factors? An Updated Narrative Review.Journal of personalized medicine · 2024Review
- Editorial: Developmental biology and endocrine research for a successful pregnancy.Frontiers in endocrinology · 2024Article
- Environmental and Genetic Traffic in the Journey from Sperm to Offspring.Biomolecules · 2023Review
- Sciadopitysin mitigates spermatological and testicular damage instigated by paraquat administration in male albino rats.Scientific reports · 2023Article
- Microplastics, a Global Issue: Human Exposure through Environmental and Dietary Sources.Foods (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAmong the factors causing male infertility, one of the most debated is the exposure to environmental contaminants. Recently, the chemical compound Bisphenol A (BPA) has drawn attention from the reproductive science community, due to its ubiquitous presence in day-to-day life. Its toxic action appears to mainly affect the male reproductive system, directly impacting male fertility. MAIN: The purpose of this review is to investigate current research data on BPA, providing an overview of the findings obtained from studies in animal and human models, as well as on its supposed mechanisms of action.
conclusionA clear understanding of BPA action mechanisms, as well as the presumed risks deriving from its exposure, is becoming crucial to preserve male fertility. The development and validation of methodologies to detect BPA toxic effects on reproductive organs can provide greater awareness of the potential threat that this chemical represents.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.