Evidence map›Paper›PMID 30660181›Full record

ArticleEuropean journal of medical research2019

Eradication of Acinetobacter baumannii/Enterobacter cloacae complex in an open proximal tibial fracture and closed drop foot correction with a multidisciplinary approach using the Taylor Spatial Frame

G Siebenbürger, B Grabein, T Schenck, C Kammerlander, W Böcker, C Zeckey

Open access · goldAbstract readCase Reports
In one paragraph

Article in European journal of medical research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

G SiebenbürgerDepartment for General, Trauma and Reconstructive Surgery, University Hospital, LMU Munich, Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377, München, Germany.
B GrabeinDepartment for Clinical Microbiology and Hospital Hygiene, University Hospital, LMU Munich, Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377, München, Germany.
T SchenckDepartment for Hand-, Plastic and Aesthetic Surgery, University Hospital, LMU Munich, Ludwig-Maximilians-Universität München, Nussbaumstr. 20, 80336, München, Germany.
C KammerlanderDepartment for General, Trauma and Reconstructive Surgery, University Hospital, LMU Munich, Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377, München, Germany.
W BöckerDepartment for General, Trauma and Reconstructive Surgery, University Hospital, LMU Munich, Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377, München, Germany.
C ZeckeyDepartment for General, Trauma and Reconstructive Surgery, University Hospital, LMU Munich, Ludwig-Maximilians-Universität München, Marchioninistr. 15, 81377, München, Germany. Christian.Zeckey@med.uni-muenchen.de.
Ludwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMulti-drug-resistant bacteria (e.g. Carbapenem-resistant Acinetobacter baumannii, extended-spectrum betalactamase or carbapenemase-producing enterobacteriaceae) are emerging in early-onset infections. So far, there is no report describing the eradication of these bacteria in a osseous infection of an open proximal tibial fracture in combination with the hexapod technology to address both osseous consolidation and closed drop foot correction. CASE PRESENTATION: After sustaining a proximal tibial fracture (Gustilo 3B), a 41-year-old man was primarily treated with open reduction and internal fixation by a locking plate and split-thickness skin graft in the home country. At the time of admission to our hospital there was a significant anterolateral soft tissue defect covered with an already-necrotic split-thickness graft and suspicious secretion. CAT and MRI scans revealed no signs of osseous healing, intramedullary distinctive osteomyelitis, as well as a large abscess zone in the dorsal compartment. Multiple wound smears showed multi-drug-resistant bacteria: Acinetobacter baumannii (Carbapenem resistant) as well as Enterobacter cloacae complex (AmpC overexpression). After implant removal, excessive osseous and intramedullary debridements using the Reamer Irrigator Aspirator (RIA

conclusionsA multidisciplinary approach with orthopaedic surgeons for debridement, planning and establishing osseous and joint correction and consolidation, plastic surgeons for microvascular muscle flaps for soft tissue defect coverage as well as clinical microbiologists for the optimized anti-infective treatment is essential in these challenging rare cases. LEVEL OF EVIDENCE: Level IV.

Indexed as

Acinetobacter InfectionsEnterobacteriaceae InfectionsAcinetobacter baumanniiAdultAnti-Bacterial AgentsDebridementDrug Resistance, Multiple, BacterialEnterobacter cloacaeExternal FixatorsFracture Fixation, InternalHumansInternal FixatorsMaleNegative-Pressure Wound TherapyOpen Fracture ReductionPeroneal NeuropathiesAnti-Bacterial AgentsAcinetobacter baumanniiAntibioticsComplicationHexapod external fixationInfectionLatissimus dorsi muscle flapLocked platingOpen fractureOutcomeProximal tibial fracture

Identifiers

PMID30660181
PMCPMC6339402
OpenAlexW2922796740

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.