ArticleClinical immunology (Orlando, Fla.)2019
Dissecting alterations in human CD8+ T cells with aging by high-dimensional single cell mass cytometry.
Article in Clinical immunology (Orlando, Fla.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Review
- Chronic inflammation as a driving factor for sarcopenia: an update on pathophysiology and future therapeutic targets.Frontiers in pharmacology · 2026Review
- General and individualized changes in T cell immunity during aging.Journal of immunology (Baltimore, Md. : 1950) · 2025Review
- Increased CD8+ tissue resident memory T cells, regulatory T cells and activated natural killer cells in systemic sclerosis lungs.Rheumatology (Oxford, England) · 2024Article
- Aging gene signature of memory CD8Immunity & ageing : I & A · 2023Article
- Human PBMC scRNA-seq-based aging clocks reveal ribosome to inflammation balance as a single-cell aging hallmark and super longevity.Science advances · 2023Article
- Implication of IL-7 receptor alpha chain expression by CD8Immunity & ageing : I & A · 2022Review
- Characterization of the effect of histone deacetylation inhibitors on CD8Journal of translational medicine · 2022Article
- Alterations in high-dimensional T-cell profile and gene signature of immune aging in HIV-infected older adults without viremia.Aging cell · 2022Article
- Immunosenescence, aging and successful aging.Frontiers in immunology · 2022Review
- Transcriptional Analysis of Total CD8Frontiers in immunology · 2022Article
- Review
- A distinct association of inflammatory molecules with outcomes of COVID-19 in younger versus older adults.Clinical immunology (Orlando, Fla.) · 2021Article
- Infectious Complications Predict Premature CD8Journal of clinical immunology · 2021Article
- Immune Cell Number, Phenotype, and Function in the Elderly with Sepsis.Aging and disease · 2021Review
- IL-7 receptor alpha defines heterogeneity and signature of human effector memory CD8Cellular immunology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
We investigated the effect of aging on the multi-dimensional characteristics and heterogeneity of human peripheral CD8
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.