ArticleNeuropsychopharmacology reports2019
Open source code for behavior analysis in rodents.
Article in Neuropsychopharmacology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed.
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- Mice Born to Mothers Fed a Diet High in Omega-6 Fatty Acids and Low in Omega-3 Fatty Acids During Pregnancy Exhibit Various Behavioral Changes Including Impaired Social Behaviors and Enhanced Recognition Memory.The Journal of nutrition · 2025Article
- Differential contribution of canonical and noncanonical NLGN3 pathways to early social development and memory performance.Molecular brain · 2024Article
- Pain-related neuronal ensembles in the primary somatosensory cortex contribute to hyperalgesia and anxiety.iScience · 2023Article
- PDZD8-deficient mice manifest behavioral abnormalities related to emotion, cognition, and adaptation due to dyslipidemia in the brain.Molecular brain · 2023Article
- Forebrain-specific conditional calcineurin deficiency induces dentate gyrus immaturity and hyper-dopaminergic signaling in mice.Molecular brain · 2022Article
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- Chd8 mutation in oligodendrocytes alters microstructure and functional connectivity in the mouse brain.Molecular brain · 2020Article
- Protrudin-deficient mice manifest depression-like behavior with abnormalities in activity, attention, and cued fear-conditioning.Molecular brain · 2020Article
- Comprehensive behavioral analysis of heterozygous Syngap1 knockout mice.Neuropsychopharmacology reports · 2019Article
- Open source code for behavior analysis in rodents.Neuropsychopharmacology reports · 2019Article
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5 authors.
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Abstract
aimWe have conducted a series of behavioral tests, which cover a broad range of behavioral domains, on various strains of genetically engineered mice. For the behavioral screening, we have been using Image J plugins that we developed for most of the tests in the battery. Our behavioral analysis system with the plugins enables systematic and automated image analysis of behavior. The plugins are freely available on the "Mouse Phenotype Database" website (http://www.mouse-phenotype.org/software.html). Here, we release the source code of the plugins in a Git repository with the aim of promoting their use and expanding their functionality.
methodsWe published the source code of the Image J plugins for behavioral analysis at Git repository (https://github.com/neuroinformatics). The source code for light/dark transition, elevated plus maze, open filed, T-maze, and fear conditioning tests was made publicly available in the repository.
conclusionsThe source code of the plugins for the behavioral tests as well as the pre-compiled binaries can be freely obtained. The open source code could promote the development and modification of the plugins for additional behavioral indices in these tests and for other behavioral tests.
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