ArticlePediatric obesity2019
Eating in the absence of hunger in young children is related to brain reward network hyperactivity and reduced functional connectivity in executive control networks.
Article in Pediatric obesity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Factors Associated with Eating in the Absence of Hunger among Children and Adolescents: A Systematic Review.Nutrients · 2022Pooled it
- The Influence of Ultraprocessed Food Consumption on Energy Intake in Emerging Adulthood: A Controlled Feeding Trial.Obesity (Silver Spring, Md.) · 2026Trial
- Altered effective connectivity between the prefrontal cortex and caudate in children with overweight and obesity.International journal of obesity (2005) · 2026Article
- Appetite Self-Regulation in Childhood: A Narrative Review and Conceptual Model of Processes and Mechanisms With Implications for Research and Practice.Nutrition reviews · 2025Review
- Exposure to gestational diabetes mellitus in utero impacts hippocampal functional connectivity in response to food cues in children.International journal of obesity (2005) · 2024Article
- Exposure to gestational diabetes mellitus in utero impacts hippocampal functional connectivity in response to food cues in children.Research square · 2024Article
- Neurodevelopmental Programming of Adiposity: Contributions to Obesity Risk.Endocrine reviews · 2024Review
- Neural correlates of appetite in adolescents.Appetite · 2023Article
- Biobehavioral susceptibility for obesity in childhood: Behavioral, genetic and neuroimaging studies of appetite.Physiology & behavior · 2023Review
- Binge-Eating Precursors in Children and Adolescents: Neurodevelopment, and the Potential Contribution of Ultra-Processed Foods.Nutrients · 2023Review
- Brain functional and structural magnetic resonance imaging of obesity and weight loss interventions.Molecular psychiatry · 2023Review
- Children's eating behaviours and related constructs: conceptual and theoretical foundations and their implications.The international journal of behavioral nutrition and physical activity · 2023Review
- Longitudinal assessment of brain structure and behaviour in youth with rapid weight gain: Potential contributing causes and consequences.Pediatric obesity · 2023Article
- Association study between hypothalamic functional connectivity, early nutrition, and glucose levels in healthy children aged 6 years: The COGNIS study follow-up.Frontiers in nutrition · 2022Article
- Trait self-control and disinhibited eating in COVID-19: The mediating role of perceived mortality threat and negative affect.Appetite · 2021Article
- Resting State Hypoconnectivity of Reward Networks in Binge Eating Disorder.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Reward-related neural correlates in adolescents with excess body weight.NeuroImage. Clinical · 2021Article
- "Food" and "non-food" self-regulation in childhood: a review and reciprocal analysis.The international journal of behavioral nutrition and physical activity · 2020Review
- Altered connectivity patterns of medial and lateral orbitofrontal cortex underlie the severity of bulimic symptoms.International journal of clinical and health psychology : IJCHPArticle
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundRecent work has implicated disinhibited eating behaviours (DEB) as a potential pathway toward obesity development in children. However, the underlying neurobiology of disinhibited eating behaviours in young, healthy weight children, prior to obesity development, remains unknown.
objectivesThis study tested the relationship between DEB and intrinsic neuronal activity and connectivity in young children without obesity.
methodsBrain networks implicated in overeating including reward, salience and executive control networks, and the default mode network were investigated. DEB was measured by the eating in the absence of hunger (EAH) paradigm with postlunch kilocalories consumed from highly palatable foods (EAH kcal) used as the predictor. Intrinsic neuronal activity within and connectivity between specified networks were measured via resting-state functional magnetic resonance imaging. Eighteen typically developing children (mean age = 5.8 years) were included.
resultsEAH kcal was positively associated with activity of the nucleus accumbens, a major reward network hub (P < 0.05, corrected). EAH kcal was negatively associated with intrinsic prefrontal cortex connectivity to the striatum (P < 0.01, corrected).
conclusionsThese results suggest that neural aspects of DEB are detectable in young children without obesity, providing a potential tool to better understand the development of obesity in this population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.