Evidence map›Paper›PMID 30659739›Full record

Trial reportPsycho-oncology2019

Dyadic yoga program for patients undergoing thoracic radiotherapy and their family caregivers: Results of a pilot randomized controlled trial.

Kathrin Milbury, Zhongxing Liao, Vickie Shannon, Smitha Mallaiah, Raghuram Nagarathna, Yisheng Li, Chunyi Yang, Cindy Carmack, Eduardo Bruera, Lorenzo Cohen

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Psycho-oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 4 pooled it
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 4 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Guideline
  2. The effect of mind-body exercise in lung cancer patients: a meta-analysis of RCTs.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Article
  10. Article
  11. Survivorship Challenges and Supportive Care in Lung Cancer.Seminars in respiratory and critical care medicine · 2025
    Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Positive Psychology Approaches to Interventions for Cancer Dyads: A Scoping Review.International journal of environmental research and public health · 2022
    Article
  17. Observational
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Kathrin MilburyThe University of Texas MD Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0003-2605-3592
Zhongxing LiaoThe University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Vickie ShannonThe University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Smitha MallaiahThe University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Raghuram NagarathnaSwami Vivekananda Yoga Anusandhana Samsthana, Bengaluru, India.
Yisheng LiThe University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Chunyi YangThe University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Cindy CarmackThe University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Eduardo BrueraThe University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Lorenzo CohenThe University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
The University of Texas MD Anderson Cancer Center · USSwami Vivekananda Yoga Anusandhana Samsthana · IN

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Dyadic yoga Program for Patients with Lung Cancer Undergoing Radiotherapy and their Family CaregiversR37CA231522 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MILBURY, KATHRIN · 2018 to 2024
$2.2M
Couple-Based Mind-Body Program for Lung Cancer Patients and their PartnersK01AT007559 · NCCIH · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI MILBURY, KATHRIN · 2013 to 2017
$652k
NCCIH NIH HHS K01 AT007559NCI NIH HHS P30 CA016672NCI NIH HHS R37 CA231522
6 · The paper itself

Abstract

objectiveThoracic radiotherapy (TRT) may result in toxicities that are associated with performance declines and poor quality of life (QOL) for patients and their family caregivers. The purpose of this randomized controlled trial was to establish feasibility and preliminary efficacy of a dyadic yoga (DY) intervention as a supportive care strategy.

methodsPatients with stage I to III non-small cell lung or esophageal cancer undergoing TRT and their caregivers (N = 26 dyads) were randomized to a 15-session DY or a waitlist control (WLC) group. Prior to TRT and randomization, both groups completed measures of QOL (SF-36) and depressive symptoms (CES-D). Patients also completed the 6-minute walk test (6MWT). Dyads were reassessed on the last day of TRT and 3 months later.

resultsA priori feasibility criteria were met regarding consent (68%), adherence (80%), and retention (81%) rates. Controlling for relevant covariates, multilevel modeling analyses revealed significant clinical improvements for patients in the DY group compared with the WLC group for the 6MWT (means: DY = 473 m vs WLC = 397 m, d = 1.19) and SF-36 physical function (means: DY = 38.77 vs WLC = 30.88; d = .66) and social function (means: DY = 45.24 vs WLC = 39.09; d = .44) across the follow-up period. Caregivers in the DY group reported marginally clinically significant improvements in SF-36 vitality (means: DY = 53.05 vs WLC = 48.84; d = .39) and role performance (means: DY = 52.78 vs WLC = 48.59; d = .51) relative to those in the WLC group.

conclusionsThis novel supportive care program appears to be feasible and beneficial for patients undergoing TRT and their caregivers. A larger efficacy trial with a more stringent control group is warranted.

Indexed as

Adaptation, PsychologicalAdultCaregiversDepressionEsophageal NeoplasmsFemaleHumansLung NeoplasmsMaleMiddle AgedPilot ProjectsQuality of LifeSocial AdjustmentYogacancerdyadic interventionfamily caregiversoncologyphysical functionquality of lifethoracic radiotherapyyoga

Identifiers

PMID30659739
PMCPMC6405285
OpenAlexW2908686035

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.