Evidence map›Paper›PMID 30659738›Full record

ReviewJournal of cellular and molecular medicine2019

Trabecular meshwork cells are a valuable resource for cellular therapy of glaucoma.

Hong Sun, Qin Zhu, Ping Guo, Yuan Zhang, Sean Tighe, Yingting Zhu

Open access · goldAbstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Long non-coding RNA SNHG11 regulates the Wnt/β-catenin signaling pathway through rho/ROCK in trabecular meshwork cells.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023
    Article
  7. All-International journal of molecular sciences · 2022
    Article
  8. Newer advances in medical management of glaucoma.Indian journal of ophthalmology · 2022
    Review
  9. Normal and glaucomatous outflow regulation.Progress in retinal and eye research · 2021
    Review
  10. Article
  11. Review
  12. Human Trabecular Meshwork Progenitors.International journal of medical sciences · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Hong SunDepartment of Ophthalmology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Qin ZhuDepartment of Ophthalmology, the Second People's Hospital of Yunnan Province (Fourth Affiliated Hospital of Kunming Medical University), Yunnan Eye Institute, Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmology (2017DG008), Provincial Innovation Team for Cataract and Ocular Fundus Disease, The Second People's Hospital of Yunnan Province (2017HC010), Expert Workstation of Yao Ke (2017IC064), Kunming, China.
Ping GuoShenzhen University School of Medicine, Shenzhen Eye Hospital, Shenzhen, China.
Yuan ZhangTissue Tech, Inc., Ocular Surface Center, Ocular Surface Research & Education Foundation, Miami, Florida.
Sean TigheTissue Tech, Inc., Ocular Surface Center, Ocular Surface Research & Education Foundation, Miami, Florida.
Yingting ZhuTissue Tech, Inc., Ocular Surface Center, Ocular Surface Research & Education Foundation, Miami, Florida.ORCID 0000-0002-3332-9713
Ocular Surface Center · USJiangsu Province Hospital · CNKunming Medical University · CNShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trabecular meshwork (TM) contains a subset of adult stem cells or progenitors that can be differentiated into corneal endothelial cells, adipocytes and chondrocytes, but not osteocytes or keratocytes. Accordingly, these progenitors can be utilized as a cell-based therapy to prevent blindness caused by glaucoma, corneal endothelial dysfunction and other diseases in general. In this review, we review in vitro expansion techniques for TM progenitors, discuss their phenotypic properties, and highlight their potential clinical applications in various ophthalmic diseases.

Indexed as

AnimalsCell- and Tissue-Based TherapyGlaucomaHumansTrabecular Meshworkglaucomaprogenitortrabecular meshwork

Identifiers

PMID30659738
PMCPMC6378204
OpenAlexW2910850643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.