ArticleCognitive, affective & behavioral neuroscience2019
Task context load induces reactive cognitive control: An fMRI study on cortical and brain stem activity.
Article in Cognitive, affective & behavioral neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Loss contexts enhance dorsolateral prefrontal interpersonal neural synchrony during successful human deceptive recommendations.Communications biology · 2026Article
- Understanding the acute and chronic effects of basketball dual-task complexity on athletes' inhibitory capacity.Scientific reports · 2026Article
- Prefrontal and Cerebellar Contributions to Semantic Memory Retrieval.Neurobiology of language (Cambridge, Mass.) · 2026Article
- Pauses, silences, and cognitive control: psycholinguistic markers of speech planning in interpreter training.Frontiers in psychology · 2026Article
- Cognitive control states and traits modulate lexical competition during word production.Scientific reports · 2025Article
- Neural Mechanisms Supporting the Relationship between Working Memory Capacity and Proactive Control.bioRxiv : the preprint server for biology · 2025Article
- Categorical and dimensional aspects of stimulant medication effects in adult patients with ADHD and healthy controls.Frontiers in pharmacology · 2024Article
- Cognitive flexibility: neurobehavioral correlates of changing one's mind.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Changes in Perceived Mental Load and Motor Performance during Practice-to-Learn and Practice-to-Maintain in Basketball.International journal of environmental research and public health · 2023Article
- Imbalanced weighting of proactive and reactive control as a marker of risk-taking propensity.PloS one · 2023Article
- The influence of context representations on cognitive control states.Cognitive research: principles and implications · 2022Article
- Decreased preparatory activation and inattention to cues suggest lower activation of proactive cognitive control among high procrastinating students.Cognitive, affective & behavioral neuroscience · 2022Article
- Article
- Cognitive and contextual factors modulating grammar learning at older ages.Frontiers in aging neuroscience · 2022Article
- Toward a formal theory of proactivity.Cognitive, affective & behavioral neuroscience · 2021Article
- The Validity of Physiological Measures to Identify Differences in Intrinsic Cognitive Load.Frontiers in psychology · 2021Review
- A Revised Framework for the Investigation of Expectation Update Versus Maintenance in the Context of Expectation Violations: The ViolEx 2.0 Model.Frontiers in psychology · 2021Article
- Adaptiveness in proactive control engagement in children and adults.Developmental cognitive neuroscience · 2020Article
- The Mouse Claustrum Is Required for Optimal Behavioral Performance Under High Cognitive Demand.Biological psychiatry · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cognitive control is a highly dynamic process that relies on flexible engagement of prefrontal areas and of neuromodulatory systems in order to adapt to changing demands. A range of internal and external factors come into play when individuals engage in a task requiring cognitive control. Here we investigated whether increased working memory (WM) demands would induce a flexible change in cognitive control mode in young healthy individuals. We developed a novel variant of the well-known AX-continuous performance task (AX-CPT). We manipulated the cognitive demands of maintaining task-relevant contextual information and studied the impact of this manipulation on behavior and brain activity. We expected that low WM load would allow for a more effortful, proactive strategy, while high WM load would induce a strategy of less effortful, stimulus-driven reactive control. In line with our hypothesis, a web-based experiment revealed that increased load was associated with more reactive behavioral responses, and this finding was independently replicated in behavioral data acquired in the MRI scanner. The results from brain activity showed that the right dorsolateral prefrontal cortex was activated by cues in the proactive mode and by probes in the reactive mode. The analysis of task-induced brain stem activity indicated that both the dopaminergic and noradrenergic systems are involved in updating context representations, and that, respectively, these systems mediate a gating signal to the control network and are involved in the dynamic regulation of task engagement.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.