Evidence map›Paper›PMID 30659436›Full record

ReviewJournal of industrial microbiology & biotechnology2019

Bioactive molecules from Nocardia: diversity, bioactivities and biosynthesis.

Dipesh Dhakal, Vijay Rayamajhi, Ravindra Mishra, Jae Kyung Sohng

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of industrial microbiology & biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Genetic Diversity ofAnimals : an open access journal from MDPI · 2025
    Article
  3. Article
  4. mBio · 2025
    Article
  5. Article
  6. The genus Nocardia as a source of new antimicrobials.npj antimicrobials and resistance · 2025
    Review
  7. Influence of rubber particle inputs on nitrogen removal efficiency of bioretention systems.Water science and technology : a journal of the International Association on Water Pollution Research · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Metabolic engineering ofEngineering microbiology · 2022
    Review
  14. Article
  15. Two chronically misdiagnosed patients infected withFrontiers in cellular and infection microbiology · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dipesh DhakalDepartment of Life Science and Biochemical Engineering, SunMoon University, 70 Sunmoon-ro 221, Tangjeong-myeon, Asan-si, Chungnam, 31460, Republic of Korea.
Vijay RayamajhiDepartment of Life Science and Biochemical Engineering, SunMoon University, 70 Sunmoon-ro 221, Tangjeong-myeon, Asan-si, Chungnam, 31460, Republic of Korea.
Ravindra MishraDepartment of Life Science and Biochemical Engineering, SunMoon University, 70 Sunmoon-ro 221, Tangjeong-myeon, Asan-si, Chungnam, 31460, Republic of Korea.
Jae Kyung SohngDepartment of Life Science and Biochemical Engineering, SunMoon University, 70 Sunmoon-ro 221, Tangjeong-myeon, Asan-si, Chungnam, 31460, Republic of Korea. sohng@sunmoon.ac.kr.ORCID http://orcid.org/0000-0003-1583-5046

Funding

National Research Foundation of Korea NRF-2017R1A2A2A05000939National Research Foundation of Korea NRF-2017R1D1A1B03036273
6 · The paper itself

Abstract

Nocardia spp. are catalase positive, aerobic, and non-motile Gram-positive filamentous bacteria. Many Nocarida spp. have been reported as unusual causes of diverse clinical diseases in both humans and animals. Therefore, they have been studied for a long time, primarily focusing on strain characterization, taxonomic classification of new isolates, and host pathophysiology. Currently, there are emerging interests in isolating bioactive molecules from diverse actinobacteria including Nocardia spp. and studying their biosynthetic mechanisms. In addition, these species possess significant metabolic capacity, which has been utilized for generating diverse functionalized bioactive molecules by whole cell biotransformation. This review summarizes the structural diversity and biological activities of compounds biosynthesized or biotransformed by Nocardia spp. Furthermore, the recent advances on biosynthetic mechanisms and genetic engineering approaches for enhanced production or structural/functional modification are presented.

Indexed as

AminoglycosidesBiological ProductsGenetic VariationGram-Positive BacteriaLactamsLactonesNocardiaOxazolesPeptides, CyclicThiazolesAminoglycosidesBiological Productsbrasilicardin ALactamsLactonesnargenicin A1nocardicinnocardithiocinnocobactinsOxazolesPeptides, CyclicThiazolesBioactive compoundsBiosynthetic mechanismBiotransformationNocardia spp.Structural modifications

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.