ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2019
Evaluation of anxiety and depression scales and quality of LIFE in cervical dystonia patients on botulinum toxin therapy and their relatives.
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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21 citing papers in PubMed, 32 citations in OpenAlex.
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- The impact of psychological distress on quality of life in isolated cervical dystonia: a case-control study.Acta neurologica Belgica · 2026Article
- Article
- Assessment of quality of life in patients with cervical dystonia and hemifacial spasm after botulinum toxin injections.Acta neurologica Belgica · 2025Article
- Development of a New Care Pathway for Depression and Anxiety in Adult-Onset Isolated Dystonia.Movement disorders clinical practice · 2023Article
- Longitudinal analysis of the relationship between motor and psychiatric symptoms in idiopathic dystonia.European journal of neurology · 2022Article
- Involvement of kynurenine pathway between inflammation and glutamate in the underlying etiopathology of CUMS-induced depression mouse model.BMC neuroscience · 2022Article
- Cognitive and Neuropsychiatric Impairment in Dystonia.Current neurology and neuroscience reports · 2022Review
- Potential interactions between cerebellar dysfunction and sleep disturbances in dystonia.Dystonia (Lausanne, Switzerland) · 2022Article
- Individual Response to Botulinum Toxin Therapy in Movement Disorders: A Time Series Analysis Approach.Toxins · 2022Article
- Treatment of Depression with Botulinum Toxin.Toxins · 2022Review
- Needs and Perceptions of Patients With Dystonia During the COVID-19 Pandemic: A Qualitative Framework Analysis of Survey Responses From Italy.Frontiers in neurology · 2022Article
- Postmarketing safety surveillance data reveals protective effects of botulinum toxin injections against incident anxiety.Scientific reports · 2021Article
- Reliability of DNMSQuest as a Screening Tool for Mood Disorders in Cervical Dystonia.Movement disorders clinical practice · 2021Article
- Personality Profile in Focal Hand Dystonia: A Cross-Sectional Study.International journal of environmental research and public health · 2021Article
- Screening for depression in movement disorders clinic.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Article
- Botulinum Neurotoxin Therapy for Depression: Therapeutic Mechanisms and Future Perspective.Frontiers in psychiatry · 2021Review
- Mental health and quality of life in patients with cervical dystonia.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Article
- Postmarketing safety surveillance data reveals antidepressant effects of botulinum toxin across various indications and injection sites.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveIn this study, quality of life and psychiatric comorbid disorders were investigated in patients with cervical dystonia and their spouses and we also investigated the effect of botulinum toxin (BTX) treatment on these parameters. MATERIAL AND
methodThirty patients with cervical dystonia (CD) on BTX treatment and their spouses (n = 30) were included. Beck Depression Scale (BDS), State-Trait Anxiety Inventory I and II (STAI-I, STAI-II), Hospital Anxiety Scale (HAS), Hospital Depression Scale (HDS) for psychiatric comorbid disease assessment, Toronto Western Spasmodic Torticollis Scale (TWSTRS) for disease activity assessment, and Craniocervical Dystonia Questionnaire (CDQ-24), Cervical Dystonia Impact Profile (CDIP-58), and Short Form 36 (SF-36) questionnaires for quality of life assessment were used. BDS, STAI-I and STAI-II, HAS, HDS, and SF-36 scales were also obtained from the spouses. The same tests were applied both before and 8 weeks after the BTX treatment.
conclusionIn our study, an increase in psychiatric comorbid disorders such as depression and anxiety was observed and the quality of life was adversely affected in all areas in patients. In the spouses of the patients, the rates of psychiatric comorbid disorders such as depression and anxiety were found to be increased when compared to healthy subjects while vitality, mental health, and general health perception were found to be negatively affected. Patients showed improvements in anxiety level, disease activity, and overall quality of life scales after BTX treatment.
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