ArticleAnnals of surgical oncology2019
Prognostic Nomogram for Disease-Specific Survival in Patients with Non-metastatic Ampullary Carcinoma After Surgery.
Article in Annals of surgical oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed.
- Histopathological subtypes independently predict survival in ampullary carcinoma: a contemporary SEER nomogram study.Journal of gastrointestinal oncology · 2026Article
- Optimizing postoperative chemotherapy for ampullary cancer: A risk-driven approach to precision care.iLIVER · 2025Article
- Intra-ampullary and Periampullary Carcinoma: Clinicopathological Comparison and Survival Outcomes.Cureus · 2024Article
- Clinicopathologic Analysis and Prognostic Factors for Survival in Patients with Operable Ampullary Carcinoma: A Multi-Institutional Retrospective Experience.Medicina (Kaunas, Lithuania) · 2024Article
- Article
- Immunohistochemical expression of beta-catenin in ampullary adenocarcinoma: a cross-sectional retrospective study.Annals of medicine and surgery (2012) · 2023Article
- Ampulla of Vater carcinoma: advancement in the relationships between histological subtypes, molecular features, and clinical outcomes.Frontiers in oncology · 2023Review
- Development and verification of prognostic nomogram for ampullary carcinoma based on the SEER database.Frontiers in oncology · 2023Article
- Machine learning models for predicting survival in patients with ampullary adenocarcinoma.Asia-Pacific journal of oncology nursing · 2022Article
- Long-term survival and pattern of recurrence in ampullary adenocarcinoma patients after curative Whipple's resection: a retrospective cohort study in the National Cancer Center in China.American journal of cancer research · 2022Article
- Prognostic Factors of Long-term Survival Following Radical Resection for Ampullary Carcinoma.Journal of gastrointestinal cancer · 2021Article
- A Prognostic Scoring System for Predicting Overall Survival of Patients with the TNM 8th Edition Stage I and II Hepatocellular Carcinoma After Surgery: A Population-Based Study.Cancer management and research · 2021Article
- The prognostic significance of inflammation-based scores in patients with ampullary carcinoma after pancreaticoduodenectomy.BMC cancer · 2020Article
- Ampullary adenocarcinoma: the current state of adjuvant therapies.Hepatobiliary surgery and nutrition · 2020Article
- A Nomogram for Individual Prediction of Poor Prognosis After Radical Surgery in Patients with Primary Pancreatic Duct Adenocarcinoma.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Ampullary carcinoma prognostic markers.Oncotarget · 2019Article
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3 authors.
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Abstract
objectiveThe aim of this study was to establish and validate an individualized nomogram for predicting disease-specific survival (DSS) in patients with non-metastatic ampullary carcinoma after surgery.
methodsThe nomogram was prepared using retrospective data from the Surveillance, Epidemiology, and End Results database, and included 2022 patients (training dataset: 1276; validation dataset: 746 patients) with non-metastatic ampullary carcinoma who were surgically treated between 2004 and 2014. Cox multivariate regression was performed to identify independent risk factors. The predictive accuracy was determined using the concordance index (C-index) and calibration curves. Results were validated internally using bootstrap resampling, and externally against the validation dataset.
resultsThe median follow-up for the training dataset was 25.5 months (range 1-143), the median survival time was 52 months [95% confidence interval (CI) 41.67-62.33], and the postoperative 1-, 3-, and 5-year DSS rates were 86.7%, 57.3%, and 47.2%, respectively. Univariate and multivariate regression analysis demonstrated that age, grade, tumor size, lymph node ratio, extension range, and histology were independent risk factors for DSS. The C-index of the internal validation dataset for predicting DSS was 0.70 (95% CI 0.68-0.72), which was superior to that of the American Joint Committee on Cancer staging, i.e. 0.64 (95% CI 0.62-0.66; p < 0.001). The 5-year DSS and median DSS time for the low-risk group were significantly greater than those for the high-risk group (p < 0.001).
conclusionOur nomogram reliably and accurately predicted DSS in patients with non-metastatic ampullary carcinoma after surgery. This model may help clinicians in their decision making.
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