ArticleProceedings of the National Academy of Sciences of the United States of America2019
Altered interplay between endoplasmic reticulum and mitochondria in Charcot-Marie-Tooth type 2A neuropathy.
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In one paragraph
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 1 pooled it
7.6field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.
- Inter-organellar Communication in Parkinson's and Alzheimer's Disease: Looking Beyond Endoplasmic Reticulum-Mitochondria Contact Sites.Frontiers in neuroscience · 2022Pooled it
- Mitochondria‑endoplasmic reticulum contact site nexus: Molecular integration, disease pathogenesis and therapeutic opportunities (Review).International journal of molecular medicine · 2026Review
- ATL2 Recruits TRAK1 to Promote Mitochondrial Transport at ER-Mitochondria Contact Sites.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Disease-causing MFN2 mutants impair mitochondrial fission dynamics by distinct DRP1 dysregulation.Cell death & disease · 2026Article
- Dynamic imbalance of mitochondria-associated ER membranes in cardiovascular disease: mechanisms, context dependence and therapeutic potential.Frontiers in cell and developmental biology · 2026Review
- Mitochondria-associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease.FEBS open bio · 2026Review
- Drug repurposing screen identifies an HRI activating compound that promotes adaptive mitochondrial remodeling in MFN2-deficient cells.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Charcot-Marie-Tooth type 2A variants of mitofusin 2 sensitize cells to apoptotic cell death.Journal of cell science · 2025Article
- Drug Repurposing Screen Identifies an HRI Activating Compound that Promotes Adaptive Mitochondrial Remodeling in MFN2-deficient Cells.bioRxiv : the preprint server for biology · 2025Article
- Mitochondria-Associated Membranes: A Key Point of Neurodegenerative Diseases.CNS neuroscience & therapeutics · 2025Review
- Cardioprotective effect of Yiqi Huoxue decoction on post-myocardial infarction injury mediated by CaFrontiers in cardiovascular medicine · 2025Article
- Dynamic interaction of REEP5-MFN1/2 enables mitochondrial hitchhiking on tubular ER.The Journal of cell biology · 2024Article
- HIV-1 and methamphetamine co-treatment in primary human astrocytes: TAARgeting ER/UPR dysfunction.NeuroImmune pharmacology and therapeutics · 2024Article
- Charcot-Marie-Tooth type 2A in vivo models: Current updates.Journal of cellular and molecular medicine · 2024Review
- Mitochondrial outer membrane protein MTUS1/ATIP1 exerts antitumor effects through ROS-induced mitochondrial pyroptosis in head and neck squamous cell carcinoma.International journal of biological sciences · 2024Article
- Janus-faced Mitofusin 2 (MFN2): mitochondria-endoplasmic reticulum shaping and tethering functions unveiled.Signal transduction and targeted therapy · 2024Article
- Sphingolipid desaturase DEGS1 is essential for mitochondria-associated membrane integrity.The Journal of clinical investigation · 2023Article
- Activating mitofusins interrupts mitochondrial degeneration and delays disease progression in SOD1 mutant amyotrophic lateral sclerosis.Human molecular genetics · 2023Article
- Role of tubulin post-translational modifications in peripheral neuropathy.Experimental neurology · 2023Review
- A small molecule M1 promotes optic nerve regeneration to restore target-specific neural activity and visual function.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 6 institutions in 4 countries.
Nathalie Bernard-MarissalBrain Mind Institute, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland; nathalie.bernard.1@univ-amu.fr bernard.schneider@epfl.ch roman.chrast@ki.se.
Gerben van HamerenINSERM U1051, Institut des Neurosciences de Montpellier, Université de Montpellier, 34295 Montpellier, France.
Manisha JunejaPeripheral Neuropathy Research Group, Department of Biomedical Sciences, University of Antwerp, 2610 Antwerp, Belgium.
Christophe PellegrinoInstitut de Neurobiologie de la Méditerranée, INSERM, Aix-Marseille Univ, 13009 Marseille, France.ORCID 0000-0002-0669-4918
Lauri LouhivuoriDepartment of Medical Biochemistry and Biophysics, Karolinska Institutet, 17177 Stockholm, Sweden.
Luca BartesaghiDepartment of Neuroscience, Karolinska Institutet, 17177 Stockholm, Sweden.
Cylia RochatBrain Mind Institute, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
Omar El MansourBrain Mind Institute, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
Jean-Jacques MédardDepartment of Neuroscience, Karolinska Institutet, 17177 Stockholm, Sweden.
Marie CroisierCentre of Interdisciplinary Electron Microscopy, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
Catherine MaclachlanCentre of Interdisciplinary Electron Microscopy, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
Olivier PoirotDepartment of Medical Genetics, University of Lausanne, 1005 Lausanne, Switzerland.
Per UhlénDepartment of Medical Biochemistry and Biophysics, Karolinska Institutet, 17177 Stockholm, Sweden.ORCID 0000-0003-1446-1062
Vincent TimmermanPeripheral Neuropathy Research Group, Department of Biomedical Sciences, University of Antwerp, 2610 Antwerp, Belgium.
Nicolas TricaudINSERM U1051, Institut des Neurosciences de Montpellier, Université de Montpellier, 34295 Montpellier, France.
Bernard L SchneiderBrain Mind Institute, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland; nathalie.bernard.1@univ-amu.fr bernard.schneider@epfl.ch roman.chrast@ki.se.
Roman ChrastDepartment of Neuroscience, Karolinska Institutet, 17177 Stockholm, Sweden; nathalie.bernard.1@univ-amu.fr bernard.schneider@epfl.ch roman.chrast@ki.se.
École Polytechnique Fédérale de Lausanne · CHInserm · FRStockholm University · SEKarolinska Institutet · SEUniversity of Antwerp · BEUniversity Hospital of Lausanne · CH
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mutations in the
Indexed as
AnimalsAxonsBiological TransportCharcot-Marie-Tooth DiseaseDisease Models, AnimalEndoplasmic ReticulumFemaleGaitLocomotionMaleMiceMice, TransgenicMitochondriaMotor NeuronsMuscle DenervationMuscle Fibers, Slow-TwitchCMT2Aendoplasmic reticulummitochondriamotoneuronsneuropathy
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.