Evidence map›Paper›PMID 30659000›Full record

ArticleBMJ case reports2019

Solid papillary thyroid carcinoma with Hashimoto's thyroiditis: description of a further case with challenging cytological features.

Franco Fulciniti, Jessica Barizzi, Pierpaolo Trimboli, Luca Giovanella

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Aggressive Types of Malignant Thyroid Neoplasms.Journal of clinical medicine · 2024
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Franco FulcinitiPathology, Institute of Pathology, Locarno, Switzerland.ORCID http://orcid.org/0000-0002-4244-1109
Jessica BarizziPathology, Institute of Pathology, Locarno, Switzerland.
Pierpaolo TrimboliDepartment of Nuclear Medicine and Thyroid Centre, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.
Luca GiovanellaDepartment of Nuclear Medicine and Thyroid Centre, Oncology Institute of Southern Switzerland, Bellinzona, Switzerland.
Institute of Oncology Research · CHIstituto Cantonale di Patologia · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Solid papillary thyroid carcinoma (SV-PTC) is a rare variant which is mainly observed in young patients with a history of exposure to ionising radiations. Neoplasms belonging to such category generally carry RET-PTC (REarranged during Transfection- Papillary Thyroid Carcinoma) fusions and seem to have a slightly worse prognosis with respect to classical and follicular variants of papillary thyroid carcinoma (PTC), though consistent prognostic and survival data are scarce. SV-PTC should be differentiated from trabecular-insular poorly differentiated thyroid carcinomas, which occur in a different age group and carry a dismal prognosis. These latter tumours do not show the typical nuclear features of PTC and show tumour necrosis with an high mitotic activity. In this report a further case of SV-PTC is described which was associated to Hashimoto's thyroiditis, a finding never described in the cytological literature up to now for SV-PTC; this association created further differential diagnostic problems. The neoplasm displayed RET-PTC1 fusion.

Indexed as

Biopsy, Fine-NeedleHashimoto DiseaseHumansMaleOncogene Proteins, FusionPrognosisProtein-Tyrosine KinasesThyroid Cancer, PapillaryThyroidectomyThyroid NeoplasmsYoung AdultOncogene Proteins, FusionProtein-Tyrosine Kinasesret-PTC fusion oncoproteins, humanendocrine cancerendocrinologyhead and neck cancerpathology

Identifiers

PMID30659000
PMCPMC6340508
OpenAlexW2909896127

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.