Evidence map›Paper›PMID 30658996›Full record

Trial reportGut2020

Reduced efficacy of low FODMAPs diet in patients with IBS-D carrying sucrase-isomaltase (

Tenghao Zheng, Shanti Eswaran, Amanda L Photenhauer, Juanita L Merchant, William D Chey, Mauro D'Amato

Registry-linked trialAbstract readLetterRandomized Controlled Trial
In one paragraph

Trial report in Gut, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05795049 (Genetic Carbohydrate Maldigestion as a Model to Study Food Hypersensitivity Mechanism and Guide Personalised Treatment Using a Non-invasive Multiparametric Test), which is not on this map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05795049 active not recruitingnot on this mapstarted 2024, after this paper: background citation

Genetic Carbohydrate Maldigestion as a Model to Study Food Hypersensitivity Mechanism and Guide Personalised Treatment Using a Non-invasive Multiparametric Test (Work Package 1)

TypeobservationalSponsorNottingham University Hospitals NHS TrustRan2024 to 2026Enrolled2,000ConditionsIrritable Bowel Syndrome (IBS), Sucrase Isomaltase DeficiencyArmsStool and saliva sample collection, Questionnaire completion
3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Innovative concepts in diet therapies in disorders of gut-brain interaction.JGH open : an open access journal of gastroenterology and hepatology · 2024
    Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Genetics of irritable bowel syndrome: shifting gear via biobank-scale studies.Nature reviews. Gastroenterology & hepatology · 2022
    Review
  14. Review
  15. Article
  16. Current perspectives on irritable bowel syndrome: a narrative review.The Journal of international medical research · 2022
    Review
  17. Review
  18. Article
  19. Sucrose intolerance in adults with common functional gastrointestinal symptoms.Proceedings (Baylor University. Medical Center) · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tenghao ZhengUnit of Clinical Epidemiology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
Shanti EswaranDivision of Gastroenterology, Michigan Medicine, Ann Arbor, Michigan, USA.
Amanda L PhotenhauerDivision of Gastroenterology, Michigan Medicine, Ann Arbor, Michigan, USA.
Juanita L MerchantDivision of Gastroenterology, University of Arizona, Tucson, Arizona, USA.
William D Chey *Division of Gastroenterology, Michigan Medicine, Ann Arbor, Michigan, USA.
Mauro D'Amato *Unit of Clinical Epidemiology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0003-2743-5197

Funding

Pilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Kanakadurga Singer · 2010 to 2026
$20.3M
NIDDK NIH HHS P30 DK089503
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diet, Carbohydrate-RestrictedAdultFemaleGenetic VariationGenotypeHumansIrritable Bowel SyndromeMaleMiddle AgedPrognosisSucrase-Isomaltase ComplexTreatment OutcomeSucrase-Isomaltase Complexcarbohydratesgenetic polymorphismsirritable bowel syndrome

Identifiers

PMID30658996
PMCPMC6984052

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.