Evidence map›Paper›PMID 30658986›Full record

ArticleDevelopment (Cambridge, England)2019

Commensal microbiota-induced redox signaling activates proliferative signals in the intestinal stem cell microenvironment.

April R Reedy, Liping Luo, Andrew S Neish, Rheinallt M Jones

Open access · bronzeAbstract read
In one paragraph

Article in Development (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Insect Gut Regeneration.Cold Spring Harbor perspectives in biology · 2022
    Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. JNK-dependent intestinal barrier failure disrupts host-microbe homeostasis during tumorigenesis.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  16. Article
  17. SecretedGut microbes
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

April R ReedyDepartment of Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Liping LuoDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.
Andrew S NeishDepartment of Pathology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Rheinallt M JonesDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA rjones5@emory.edu.ORCID 0000-0002-0415-9487
Emory University · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Microbial Influence on Mucosal HomeostasisR01AI064462 · NIAID · EMORY UNIVERSITY · PI NEISH, ANDREW S · 2006 to 2022
$5.5M
PATHOBIOLOGY OF MUCOSAL/EPITHELIAL DISEASET32DK007771 · NIDDK · EMORY UNIVERSITY · PI NEISH, ANDREW S · 1999 to 2015
$2.0M
Intestinal cell response to bacterial apoptotic signalsR01DK071604 · NIDDK · EMORY UNIVERSITY · PI NEISH, ANDREW S · 2007 to 2011
$1.5M
The molecular mechanisms of intestinal homeostasis.R01DK098391 · NIDDK · EMORY UNIVERSITY · PI JONES, RHEINALLT MELFYN · 2014 to 2017
$1.4M
Control of Epithelial Proliferation by the MicrobiotaR01CA179424 · NCI · EMORY UNIVERSITY · PI JONES, RHEINALLT MELFYN, NEISH, ANDREW S · 2014 to 2017
$1.3M
NCI NIH HHS R01 CA179424NIAID NIH HHS R01 AI064462NIDDK NIH HHS R01 DK071604NIDDK NIH HHS R01 DK098391NIDDK NIH HHS T32 DK007771NIH HHS P40 OD018537
6 · The paper itself

Abstract

A distinct taxon of the

Indexed as

AnimalsDrosophila melanogasterEnterocytesGastrointestinal MicrobiomeLactiplantibacillus plantarumOxidation-ReductionReactive Oxygen SpeciesSignal TransductionStem Cell NicheStem CellsReactive Oxygen SpeciesDrosophilaJAK/STATNon-cell autonomousNrf2ROSStem cell

Identifiers

PMID30658986
PMCPMC6382009
OpenAlexW2909426350

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.