Evidence map›Paper›PMID 30658629›Full record

Trial reportHealth and quality of life outcomes2019

The impact of an exercise program on quality of life in older breast cancer survivors undergoing aromatase inhibitor therapy: a randomized controlled trial.

Thais R S Paulo, Fabricio E Rossi, Juliana Viezel, Giuliano T Tosello, Sylvia C Seidinger, Regina R Simões, Ruffo de Freitas, Ismael F Freitas

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Health and quality of life outcomes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07460492 (Therapeutic Plyometric-Based Strength-Endurance Exercise Program for Breast Cancer Patients and Survivors to Improve Quality of Life and Physical and Mental Function), which is not on this map. Cited by 65 papers, 25 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 25 pooled it
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07460492 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Therapeutic Plyometric-Based Strength-Endurance Exercise Program for Breast Cancer Patients and Survivors to Improve Quality of Life and Physical and Mental Function

TypeinterventionalSponsorUniversity of VigoRan2026 to 2027Enrolled51ConditionsNeoplams, Patients, Cancer SurvivorsArmsPlyometric Strength-Endurance Training, Conventional Strength Training
3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 25 syntheses or guidelines pooled it, 117 citations in OpenAlex.

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  14. Physical activity and pain in people with cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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  18. The role of exercise for pain management in adults living with and beyond cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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  20. Efficacy of physical therapy interventions on quality of life and upper quadrant pain severity in women with post-mastectomy pain syndrome: a systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Pooled it

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Thais R S PauloState University of Sao Paulo, UNESP, School of Technology and Sciences, Rua Roberto Simonsen, 305, Presidente Prudente, Sao Paulo, CEP 19060-900, Brazil. thais.reis.silva@hotmail.com.
Fabricio E RossiState University of Sao Paulo, UNESP, School of Technology and Sciences, Rua Roberto Simonsen, 305, Presidente Prudente, Sao Paulo, CEP 19060-900, Brazil.
Juliana ViezelState University of Sao Paulo, UNESP, School of Technology and Sciences, Rua Roberto Simonsen, 305, Presidente Prudente, Sao Paulo, CEP 19060-900, Brazil.
Giuliano T ToselloFederal University of São Paulo, USP, Sao Paulo, Brazil.
Sylvia C SeidingerState University of Sao Paulo, UNESP, School of Technology and Sciences, Rua Roberto Simonsen, 305, Presidente Prudente, Sao Paulo, CEP 19060-900, Brazil.
Regina R SimõesFederal University of Triângulo Mineiro, UFTM, Uberaba, Brazil.
Ruffo de FreitasFederal University of Goias, UFG, Goiânia, Brazil.
Ismael F FreitasState University of Sao Paulo, UNESP, School of Technology and Sciences, Rua Roberto Simonsen, 305, Presidente Prudente, Sao Paulo, CEP 19060-900, Brazil.
Universidade de São Paulo · BRUniversidade Estadual Paulista (Unesp) · BRUniversidade Federal de Goiás · BRUniversidade Federal de São Paulo · BRUniversidade Federal do Triângulo Mineiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study evaluated the impact of an exercise program on quality of life in older breast cancer survivors undergoing aromatase inhibitor therapy.

methodsOlder breast cancer survivors were randomized into two groups: combined training: resistance + aerobic exercise program for nine months (n = 18) or control group (n = 18). Quality of life was assessed by the questionnaires SF36, EORTC QLQ-C30, and EORTC QLQ-BR23 at baseline, and at three, six, and nine months. The exercise group performed 40 min of resistance exercises on machines followed by 30 min of aerobic training on a treadmill 3x/wk. Repeated measures ANOVA was used to compare the groups over time.

resultsSignificant time x group interactions and moderate to high effect sizes were found for physical functioning, physical health, bodily pain, general health perception, vitality, social functioning, fatigue, sleep disturbance, body image, and upset by hair loss, favoring the exercise group.

conclusionThis study demonstrated the potential benefits and high clinical relevance of exercise programs to improve quality of life in older breast cancer survivors undergoing aromatase inhibitor therapy.

Indexed as

ExerciseQuality of LifeAgedAnalysis of VarianceAromatase InhibitorsBreast NeoplasmsCancer SurvivorsExercise TherapyFatigueFemaleHumansMiddle AgedResistance TrainingSurveys and QuestionnairesSurvivorsAromatase InhibitorsBreast cancerCombined exerciseHormone therapyMenopausePhysical activityPublic health

Identifiers

PMID30658629
PMCPMC6339353
OpenAlexW2917150406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.