Evidence map›Paper›PMID 30658600›Full record

ArticleBMC cancer2019

Epidemiological characteristics, clinical outcomes and management patterns of metastatic breast cancer patients in routine clinical care settings of Greece: Results from the EMERGE multicenter retrospective chart review study.

Athanasios Kotsakis, Alexandros Ardavanis, Georgios Koumakis, Epameinondas Samantas, Amanta Psyrri, Christos Papadimitriou

Abstract readMulticenter Study
In one paragraph

Article in BMC cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Athanasios KotsakisDepartment of Medical Oncology, University General Hospital of Heraklion Crete Voutes, 711 10, Iraklio, Greece.
Alexandros Ardavanis1st Department of Medical Oncology, Agios Savvas Anticancer Hospital, 171 Alexandras Av, 115 22, Athens, Greece.
Georgios Koumakis2nd Department of Medical Oncology, Agios Savvas Anticancer Hospital, 171 Alexandras Av, 115 22, Athens, Greece.
Epameinondas Samantas3rd Department of Medical Oncology, Agii Anargiri Cancer Hospital, Kaliftaki 145, 14564 N. Kifissia, Athens, Greece.
Amanta PsyrriMedical Oncology Unit, ATTIKON University Hospital, 1 Rimini St, 124 62, Athens, Greece.
Christos PapadimitriouOncology Unit, 2nd Department of Surgery, Aretaieion Hospital, 76 Vas. Sofias Av, 115 28, Athens, Greece. chr_papadim@yahoo.gr.ORCID http://orcid.org/0000-0001-8084-0445

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe "EMERGE" study, aimed to capture real-life management patterns and outcomes in metastatic breast cancer (MBC) in Greece, also accounting for hormone (HR) and human epidermal growth factor receptor 2 (HER2) status.

methods"EMERGE" was a multicenter, retrospective cohort study of adult MBC patients diagnosed between 01-Janaury-2010 and 30-June-2012, either de novo or having progressed from a non-metastatic state. Patient data, including treatment patterns and outcomes, were mainly abstracted through medical chart review.

results386 patients were enrolled by 16 hospital-based oncologists between 12-March-2013 and 31-March-2015. The median look-back period was 29.1 months. At MBC diagnosis, 56.1% of the patients were HR

conclusions"EMERGE" demonstrates differences between HR/HER2 subtypes in clinical outcomes and divergence from evidence-based guideline recommendations for MBC management, especially as it pertains to the HR STUDY REGISTRATION: The study has been registered on the electronic Registry of Non-Interventional Studies (RNIS) posted on the website of the Hellenic Association of Pharmaceutical Companies (SFEE): https://www.dilon.sfee.gr/studiesp_d.php?meleti_id=NIS-OGR-XXX-2012/1.

Indexed as

AgedBreast NeoplasmsFemaleGreeceHumansIncidenceKaplan-Meier EstimateMiddle AgedNeoplasm MetastasisOutcome Assessment, Health CareProportional Hazards ModelsRetrospective StudiesGreeceHormone receptorHuman epidermal growth factor receptor 2Metastatic breast cancerOverall survivalProgression-free survivalTreatment patterns

Identifiers

PMID30658600
PMCPMC6339387

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.