Evidence map›Paper›PMID 30658574›Full record

ArticleBMC cardiovascular disorders2019

Clinical results of bioresorbable drug-eluting scaffolds in short and long coronary artery lesions using the PSP technique.

Christine Reichart, Jochen Wöhrle, Sinisa Markovic, Wolfgang Rottbauer, Julia Seeger

Registry-linked trialOpen access · goldAbstract readComparative Study
In one paragraph

Article in BMC cardiovascular disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02162056 (Coronary and Structural Interventions Ulm - Bioresorbable Vascular Scaffold), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02162056 nacompletednot on this map

Coronary and Structural Interventions Ulm - Bioresorbable Vascular Scaffold

TypeinterventionalSponsorUniversity of UlmRan2013 to 2018Enrolled326ConditionsCoronary Artery Disease, Ischemic Heart Disease, Stable Angina, Unstable AnginaArmsuse of bioresorbable vascular scaffolds
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Christine ReichartDepartment of Internal Medicine II, University Hospital of Ulm, Ulm, Germany.
Jochen WöhrleHead Interventional Cardiology Research Group, University Hospital of Ulm, Albert-Einstein-Allee, 23 89081, Ulm, Germany. jochen.wohrle@t-online.de.ORCID 0000-0002-9915-1815
Sinisa MarkovicDepartment of Internal Medicine II, University Hospital of Ulm, Ulm, Germany.
Wolfgang RottbauerDepartment of Internal Medicine II, University Hospital of Ulm, Ulm, Germany.
Julia SeegerDepartment of Internal Medicine II, University Hospital of Ulm, Ulm, Germany.
University Hospital Ulm · DEUniversität Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundData on bioresorbable vascular scaffolds (BVS) for the treatment of long lesions are limited. We studied the use of BVS-Absorb in routine clinical practice and compared the outcome of long lesions with short lesions. Implantation of drug-eluting scaffolds without PSP-technique (predilation, proper sizing and postdilation) is associated with an increased thrombotic risk. We compared the long-term outcome up to 36 months of patients with short (< 20 mm) and long (≥20 mm) coronary artery lesions after implantation of bioresorbable vascular scaffolds (BVS) via PSP-technique.

methodsThree hundred twenty-six patients with 424 lesions were enrolled in this prospective study and underwent percutaneous coronary intervention with the Absorb BVS. Clinical follow-up was scheduled after 12, 24 and 36 months. In all lesions the PSP-technique was used. The device oriented composite endpoint (DOCE) was defined as cardiac death, myocardial infarction (MI) not clearly related to a non-target vessel and target lesion revascularization (TLR).

resultsKaplan-Meier estimates for DOCE after 12 months were 2.63% for short lesions and 8.09% for long lesions (p = 0.0131), 5.51% vs. 11.35% (p = 0.0503) after 24 months and 8.00% vs. 18.00% (p = 0.0264) after 36 months of clinical follow-up. Kaplan-Meier estimates for TLR after 12 months were 1.46% for short and 7.69% for long lesions (p = 0.0012), 2.06% vs. 8.75% after 24 months (p = 0.0027) and 4.96% vs. 9.59% after 36 months of follow-up (p = 0.0109). Scaffold thrombosis rates were low.

conclusionsIn long lesions compared to short ones the bioresorbable scaffold Absorb implanted with the proper PSP technique Absorb has significant higher rates of DOCE. THE LEVEL OF EVIDENCE: Is 3 (non-random sample).

Indexed as

Absorbable ImplantsCoated Materials, BiocompatibleAgedAngioplasty, Balloon, CoronaryCardiovascular AgentsCoronary Artery DiseaseCoronary ThrombosisEverolimusFemaleHumansMaleMiddle AgedMyocardial InfarctionProsthesis DesignRisk AssessmentRisk FactorsCardiovascular AgentsCoated Materials, BiocompatibleEverolimusAbsorb scaffoldFollow-upLong lesionsPSP-technique

Identifiers

PMID30658574
PMCPMC6339442
OpenAlexW2913485051

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.