Evidence map›Paper›PMID 30658415›Full record

ArticleMolecules (Basel, Switzerland)2019

Synthesis, In Silico, and In Vitro Evaluation of Long Chain Alkyl Amides from 2-Amino-4-Quinolone Derivatives as Biofilm Inhibitors.

Mariana Paola Espinosa-Valdés, Sara Borbolla-Alvarez, Ana Elena Delgado-Espinosa, Juan Francisco Sánchez-Tejeda, Anabelle Cerón-Nava, Osvaldo Javier Quintana-Romero, Armando Ariza-Castolo, Diego Fernando García-Del Río, Marco A Loza-Mejía

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Structural modification of theMicrobiology (Reading, England) · 2023
    Article
  4. Heterocycles in Medicinal Chemistry.Molecules (Basel, Switzerland) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mariana Paola Espinosa-ValdésFacultad de Ciencias Químicas, Universidad La Salle-México. Av. Benjamin Franklin 45, Cuauhtémoc, Mexico City 06140, Mexico. mariana-espinosa@lasallistas.org.mx.
Sara Borbolla-AlvarezFacultad de Ciencias Químicas, Universidad La Salle-México. Av. Benjamin Franklin 45, Cuauhtémoc, Mexico City 06140, Mexico. sara.borbolla@lasallistas.org.mx.
Ana Elena Delgado-EspinosaFacultad de Ciencias Químicas, Universidad La Salle-México. Av. Benjamin Franklin 45, Cuauhtémoc, Mexico City 06140, Mexico. ana.delgado@lasallistas.org.mx.
Juan Francisco Sánchez-TejedaFacultad de Ciencias Químicas, Universidad La Salle-México. Av. Benjamin Franklin 45, Cuauhtémoc, Mexico City 06140, Mexico. juansanchez@lasallistas.org.mx.
Anabelle Cerón-NavaFacultad de Ciencias Químicas, Universidad La Salle-México. Av. Benjamin Franklin 45, Cuauhtémoc, Mexico City 06140, Mexico. anabelle.ceron@lasalle.mx.
Osvaldo Javier Quintana-RomeroDepartamento de Química Orgánica, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV-IPN), Av. Instituto Politécnico Nacional 2508, Mexico City 07360, Mexico. javo_omnosnoa@hotmail.com.
Armando Ariza-CastoloDepartamento de Química Orgánica, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV-IPN), Av. Instituto Politécnico Nacional 2508, Mexico City 07360, Mexico. aariza@cinvestav.mx.ORCID 0000-0003-2799-0764
Diego Fernando García-Del RíoFacultad de Ciencias Químicas, Universidad La Salle-México. Av. Benjamin Franklin 45, Cuauhtémoc, Mexico City 06140, Mexico. diegodoku@gmail.com.
Marco A Loza-MejíaFacultad de Ciencias Químicas, Universidad La Salle-México. Av. Benjamin Franklin 45, Cuauhtémoc, Mexico City 06140, Mexico. marcoantonio.loza@lasalle.mx.ORCID 0000-0002-8449-0806

Funding

Universidad La Salle SAL-05/11
6 · The paper itself

Abstract

Infection from multidrug resistant bacteria has become a growing health concern worldwide, increasing the need for developing new antibacterial agents. Among the strategies that have been studied, biofilm inhibitors have acquired relevance as a potential source of drugs that could act as a complement for current and new antibacterial therapies. Based on the structure of 2-alkyl-3-hydroxy-4-quinolone and

Indexed as

Computer Simulation4-QuinolonesAmidesBiofilmsCatalytic DomainLigandsMolecular Docking SimulationMolecular Dynamics SimulationProton Magnetic Resonance SpectroscopyPseudomonas aeruginosaQuorum SensingStaphylococcus aureus4-QuinolonesAmidesLigandsbiofilmmolecular dockingmolecular dynamicsquinolonesquorum sensing

Identifiers

PMID30658415
PMCPMC6359591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.