Evidence map›Paper›PMID 30658250›Full record

ArticleJournal of the mechanical behavior of biomedical materials2019

Crack initiation from a clinically relevant notch in a highly-crosslinked UHMWPE subjected to static and cyclic loading.

Abhi Sirimamilla, Clare M Rimnac

Abstract read
In one paragraph

Article in Journal of the mechanical behavior of biomedical materials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Abhi SirimamillaMicrosoft Hardware Group, One Microsoft Way, Redmond, WA 98052, United States. Electronic address: abhisiri@microsoft.com.
Clare M RimnacMechanical and Aerospace Engineering Department, Case Western Reserve University, Cleveland, OH 44106, United States. Electronic address: clare.rimnac@case.edu.

Funding

TRAINING PROGRAM IN MUSCULOSKELETAL RESEARCHT32AR007505 · NIAMS · CASE WESTERN RESERVE UNIVERSITY · PI TRIOLO, RONALD J · 1986 to 2023
$6.3M
Constitutive Model for Polyethylenes in Joint ComponentsR01AR047192 · NIAMS · CASE WESTERN RESERVE UNIVERSITY · PI RIMNAC, CLARE M · 2001 to 2007
$1.5M
NIAMS NIH HHS R01 AR047192NIAMS NIH HHS T32 AR007505
6 · The paper itself

Abstract

Crosslinked Ultra High Molecular Weight Polyethylene (UHMWPE), which is used as a bearing material in total joint replacement components, is subjected to static and cyclic loads in vivo. Resistance to crack initiation from a notch as a function of static and cyclic loads is not well understood for crosslinked UHMWPE. This study estimated the resistance of crosslinked UHMWPE (crosslinked with 100 kGy gamma radiation and remelted to extinguish free radicals) to crack initiation for a clinically relevant notch under both static and cyclic loading conditions. For cyclic loading, four frequencies were applied with a sine waveform and two frequencies were applied with a square waveform to independently estimate the effect of frequency and rate of loading on crack initiation. Crack initiation time and cycles to crack initiation were determined. Crack initiation time for fatigue loading conditions was substantially lower compared to static loading conditions. Crack initiation time decreased with an increase in test frequency. A square wave resulted in shorter crack initiation time compared to a sine wave. The results suggest that crosslinked UHMWPE is more resistant to crack initiation from a notch under static loading conditions compared to fatigue loading conditions.

Indexed as

Materials TestingMechanical PhenomenaHumansPolyethylenesStress, MechanicalWeight-BearingPolyethylenesultra-high molecular weight polyethyleneCrosslink densityFatigueFatigue crack initiationFrequencyNotch rootPolymerR-ratio

Identifiers

PMID30658250
PMCPMC6409198

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.