Evidence map›Paper›PMID 30658123›Full record

ArticleJournal of virological methods2019

Prospective evaluation of diagnostic tools for respiratory viruses in children and adults.

L Busson, M Bartiaux, S Brahim, D Konopnicki, N Dauby, M Gérard, P De Backer, K Van Vaerenbergh, B Mahadeb, M De Foor and 5 more

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of virological methods, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

L BussonDepartment of Microbiology, Laboratoire des Hôpitaux Universitaires Bruxellois, Brussels, Belgium. Electronic address: laurent.busson@lhub-ulb.be.
M BartiauxDepartment of Emergency Medicine, Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxelles, Brussels, Belgium.
S BrahimDepartment of Emergency Medicine, Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxelles, Brussels, Belgium.
D KonopnickiDepartment of Infectious Diseases, Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxelles, Brussels, Belgium.
N DaubyDepartment of Infectious Diseases, Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxelles, Brussels, Belgium.
M GérardDepartment of Infectious Diseases, Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxelles, Brussels, Belgium.
P De BackerPediatric Department, Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxelles, Brussels, Belgium.
K Van VaerenberghPediatric Department, Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxelles, Brussels, Belgium.
B MahadebDepartment of Microbiology, Laboratoire des Hôpitaux Universitaires Bruxellois, Brussels, Belgium.
M De FoorDepartment of Microbiology, Laboratoire des Hôpitaux Universitaires Bruxellois, Brussels, Belgium.
M WautierDepartment of Molecular Diagnostic, Laboratoire des Hôpitaux Universitaires Bruxellois, Brussels, Belgium.
O VandenbergDepartment of Microbiology, Laboratoire des Hôpitaux Universitaires Bruxellois, Brussels, Belgium; Infectious Diseases Epidemiological Unit, Public Health School, Université Libre de Bruxelles, Brussels, Belgium.
P MolsDepartment of Emergency Medicine, Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxelles, Brussels, Belgium.
J LevyPediatric Department, Centre Hospitalier Universitaire Saint-Pierre, Université Libre de Bruxelles, Brussels, Belgium.
M HallinDepartment of Microbiology, Laboratoire des Hôpitaux Universitaires Bruxellois, Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo compare the performances of molecular and non-molecular tests to diagnose respiratory viral infections and to evaluate the pros and contras of each technique.

methodsTwo hundred ninety-nine respiratory samples were prospectively explored using multiplex molecular techniques (FilmArray Respiratory Panel, Clart Pneumovir), immunological techniques (direct fluorescent assay, lateral flow chromatography) and cell cultures.

findingsMolecular techniques permitted the recovery of up to 50% more respiratory pathogens in comparison to non-molecular methods. FilmArray detected at least 30% more pathogens than Clart Pneumovir which could be explained by the differences in their technical designs. The turnaround time under 2 hours for the FilmArray permitted delivery of results when patients were still in the emergency room.

Indexed as

Cell Culture TechniquesCell LineFemaleFluorescent Antibody TechniqueHumansInfantMaleMiddle AgedMolecular Diagnostic TechniquesProspective StudiesRespiratory Tract InfectionsSensitivity and SpecificityVirus DiseasesVirusesCell cultureClart PneumovirFilmArray Respiratory PanelImmunofluorescenceLateral flow chromatographyRespiratory viruses

Identifiers

PMID30658123
PMCPMC7119678

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.