Evidence map›Paper›PMID 30658109›Full record

ArticleCell chemical biology2019

Role of Bile in Infectious Disease: the Gall of 7α-Dehydroxylating Gut Bacteria.

Tor Savidge, Joseph A Sorg

Abstract readComment
In one paragraph

Article in Cell chemical biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Tor SavidgeDepartment of Pathology & Immunology, Baylor College of Medicine, Houston TX, 77030, USA; Texas Children's Microbiome Center, Texas Children's Hospital, Houston TX, 77030, USA. Electronic address: tor.savidge@bcm.edu.
Joseph A SorgDepartment of Biology, Texas A&M University, College Station TX, 77843, USA.

Funding

Decoding Antibiotic-induced Susceptibility to Clostridium difficile InfectionU01AI124290 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI BRITTON, ROBERT A, GAREY, KEVIN W · 2016 to 2020
$7.9M
Mechanisms of Clostridium difficile spore germinationR01AI116895 · NIAID · TEXAS A&M UNIVERSITY · PI SORG, JOE · 2015 to 2024
$3.9M
Allosteric therapy of the Clostridium difficile toxinsR01AI100914 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI SAVIDGE, TOR C. · 2012 to 2016
$1.9M
NIAID NIH HHS R01 AI100914NIAID NIH HHS R01 AI116895NIAID NIH HHS U01 AI124290
6 · The paper itself

Abstract

Local antibiotics and quorum sensors produced by gut bacteria regulate microbiota community structure and guard against pathogens. In this issue of Cell Chemical Biology, Kang et al. (2019) guide us through a reciprocal host-antimicrobial interplay that redefines our understanding of Clostridioides (Clostridium) difficile pathogenesis.

Indexed as

Clostridioides difficileMicrobiotaAnti-Bacterial AgentsBileBile Acids and SaltsAnti-Bacterial AgentsBile Acids and Salts

Identifiers

PMID30658109
PMCPMC6542261

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.