Evidence map›Paper›PMID 30658043›Full record

ArticleAnnals of the American Thoracic Society2019

Developing Inhaled Antibiotics in Cystic Fibrosis: Current Challenges and Opportunities.

Dave P Nichols, Anthony G Durmowicz, Ann Field, Patrick A Flume, Donald R VanDevanter, Nicole Mayer-Hamblett

Abstract read
In one paragraph

Article in Annals of the American Thoracic Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Tobramycin enhancesProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Review
  6. Insights onMicroorganisms · 2024
    Article
  7. Review
  8. Article
  9. Role of inhaled antibiotics in the era of highly effective CFTR modulators.European respiratory review : an official journal of the European Respiratory Society · 2023
    Review
  10. Review
  11. Article
  12. Review
  13. Drugs, Drugs, Drugs: Current Treatment Paradigms in Cystic Fibrosis Airway Infections.Journal of the Pediatric Infectious Diseases Society · 2022
    Review
  14. Article
  15. A new path for CF clinical trials through the use of historical controls.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2022
    Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Building global development strategies for cf therapeutics during a transitional cftr modulator era.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dave P Nichols1 Cystic Fibrosis Therapeutics Development Network Coordinating Center, Department of Pediatrics, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, Washington.
Anthony G Durmowicz2 Cystic Fibrosis Foundation, Bethesda, Maryland.
Ann Field2 Cystic Fibrosis Foundation, Bethesda, Maryland.
Patrick A Flume3 Department of Medicine and Pediatrics, Medical University of South Carolina, Charleston, South Carolina; and.
Donald R VanDevanter4 Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Nicole Mayer-Hamblett1 Cystic Fibrosis Therapeutics Development Network Coordinating Center, Department of Pediatrics, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, Washington.

Funding

Translational Research Center to Expedite Novel Therapies in Cystic FibrosisP30DK089507 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI Christopher Hooper Goss, Lucas R Hoffman · 2010 to 2026
$21.4M
A prospective trial of oral azithromycin when added to inhaled tobramycin in CFR01HL124053 · NHLBI · SEATTLE CHILDREN'S HOSPITAL · PI NICHOLS, DAVID PAUL · 2015 to 2019
$2.8M
NHLBI NIH HHS R01 HL124053NIDDK NIH HHS P30 DK089507
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Administration, InhalationAnti-Bacterial AgentsCystic FibrosisDrug DevelopmentHumansPseudomonas aeruginosaPseudomonas InfectionsAnti-Bacterial Agents

Identifiers

PMID30658043
PMCPMC6491060

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.