SynthesisPLoS neglected tropical diseases2019
A systematic review and meta-analysis of the prevalence of osteoarticular brucellosis.
Synthesis in PLoS neglected tropical diseases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- Follow-up outcomes of asymptomatic brucellosis: a systematic review and meta-analysis.Emerging microbes & infections · 2023Pooled it
- Dual-targeting oral nanoparticle mucosal vaccine against brucella infection: co-targeting M cells and dendritic cells.Journal of nanobiotechnology · 2026Article
- Development of a predictive model based on ultrasonographic features of brucella-associated periarthritis of the shoulder.Frontiers in cellular and infection microbiology · 2026Article
- Seroprevalence of Brucellosis in Cattle, Sheep, and Goats in the Southeastern Region of Bangladesh.Veterinary medicine international · 2026Article
- Seroprevalence and risk factors for Brucella species and Coxiella burnetii exposure in a cross-sectional serosurvey of occupationally exposed groups in peri-urban Lomé, Togo.PLoS neglected tropical diseases · 2026Article
- The atypical quorum sensing system of classicalJournal of bacteriology · 2025Review
- Bioinformatic analysis of brucellosis and construction of a diagnostic model based on key genes.Scientific reports · 2025Article
- Exploring the status of brucellosis in pregnant women presented with febrile illness at different healthcare facilities of Vehari and Lodhran zones of Pakistan.PLoS neglected tropical diseases · 2025Article
- Delayed diagnosis of pediatric brucellosis: a case study and literature review.Annals of medicine and surgery (2012) · 2025Article
- Review
- Zoonotic infections of the Canadian Arctic.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025Review
- Human Brucellosis in the Rural and Urban Population of Pakistan: Seroprevalence, Risk Factors, and Clinical Manifestations.Current microbiology · 2025Article
- MRI findings and classification of brucella spondylitis: a China multicenter study.European journal of medical research · 2024Article
- The relationship betweenNorthern clinics of Istanbul · 2024Article
- What Could Lead to the Production of Anti-Rheumatoid Antibodies in Patients with Brucellosis Spondylodiscitis: Possible Causes.Medical journal of the Islamic Republic of Iran · 2024Article
- Epidemiology of brucellosis in Mazandaran, North of Iran in a nine-year period (2009-2017).Caspian journal of internal medicine · 2024Article
- Risk perception and preventive behaviors related to brucellosis among Iranian livestock farmers.Health science reports · 2023Article
- Brucella-infected abdominal aortic aneurysm: management strategies for an uncommon aneurysm.Frontiers in medicine · 2023Article
- Case Report: Metagenomic Next-Generation Sequencing Confirmed a Case of Spine Infection withInfection and drug resistance · 2023Article
- Facing the Human and Animal Brucellosis Conundrums: The Forgotten Lessons.Microorganisms · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundInfection of bones and joints remains one of the most commonly described complications of brucellosis in humans and is predominantly reported in all ages and sexes in high-risk regions, such as the Middle East, Asia, South and Central America, and Africa. We aimed to systematically review the literature and perform a meta-analysis to estimate the global prevalence of osteoarticular brucellosis (OAB). METHODOLOGY: Major bibliographic databases were searched using keywords and suitable combinations. All studies reporting the incidence and clinical manifestations of osteoarticular brucellosis in humans, and demonstrated by two or more diagnostic methods (bacteriological, molecular, serological, and/or radiographic) were included. Random model was used, and statistical significance was set at 0.05. PRINCIPAL
findingsA total of 56 studies met the inclusion criteria and were included in the systematic review and meta-analysis. There was an evidence of geographical variation in the prevalence of osteoarticular disease with estimates ranging from 27% in low-risk regions to 36% in high-risk regions. However, the difference was not significant. Thus, brucellosis patients have at least a 27% chance of developing osteoarticular disease.
conclusionsThe prevalence of OAB is not dependent on the endemicity of brucellosis in a particular region. Hence, further research should investigate the potential mechanisms of OAB, as well as the influence of age, gender, and other socioeconomic factor variations in its global prevalence, as this may provide insight into associated exposure risks and management of the disease.
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