Evidence map›Paper›PMID 30657406›Full record

ArticleSubstance use & misuse2019

The Stimulant Selective Severity Assessment: A replication and exploratory extension of the Cocaine Selective Severity Assessment.

Robrina Walker, Thomas F Northrup, John Tillitski, Ira Bernstein, Tracy L Greer, Madhukar H Trivedi

Registry-linked trialAbstract read
In one paragraph

Article in Substance use & misuse, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06073340 (Observational Longitudinal Study of Individuals With Stimulant Use Disorder), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06073340 terminatednot on this mapstarted 2023, after this paper: background citation

Observational Longitudinal Study of Individuals With Stimulant Use Disorder: Research and Development of a Biosignature

TypeobservationalSponsorUniversity of Texas Southwestern Medical CenterRan2023 to 2025Enrolled72ConditionsStimulant Use, Stimulant-Related Disorder, Healthy
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Guideline
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Robrina Walkera Department of Psychiatry , University of Texas Southwestern Medical Center , Dallas , Texas , USA.
Thomas F Northrupb Department of Family and Community Medicine , The University of Texas Health Science Center at Houston, McGovern Medical School , Houston , Texas , USA.
John Tillitskia Department of Psychiatry , University of Texas Southwestern Medical Center , Dallas , Texas , USA.
Ira Bernsteinc Department of Clinical Sciences , University of Texas Southwestern Medical Center , Dallas , Texas , USA.
Tracy L Greera Department of Psychiatry , University of Texas Southwestern Medical Center , Dallas , Texas , USA.
Madhukar H Trivedia Department of Psychiatry , University of Texas Southwestern Medical Center , Dallas , Texas , USA.
The University of Texas Southwestern Medical Center · USThe University of Texas Health Science Center at Houston · US

Funding

Project-004UG1DA020024 · NIDA · UT SOUTHWESTERN MEDICAL CENTER · PI Steven J Shoptaw, MADHUKAR H. TRIVEDI · 2015 to 2026
$71.6M
Concept ProjectU10DA020024 · NIDA · UT SOUTHWESTERN MEDICAL CENTER · PI TRIVEDI, MADHUKAR H. · 2005 to 2015
$22.6M
NIDA NIH HHS U10 DA020024NIDA NIH HHS UG1 DA020024
6 · The paper itself

Abstract

backgroundCocaine and methamphetamine have similar withdrawal symptoms and many individuals concurrently use both substances; however, no measures concurrently assess withdrawal from multiple stimulants.

objectivesThis study's aim was to explore the Stimulant Selective Severity Assessment (SSSA), a modified version of the Cocaine Selective Severity Assessment (CSSA), in a sample of stimulant users to determine if it can assess withdrawal symptoms in users of one or more stimulants.

methodsBaseline data were analyzed from the STimulant Reduction Intervention using Dosed Exercise trial, a multisite randomized clinical trial that evaluated exercise versus health education on drug use outcomes in individuals with stimulant use disorders. Data were analyzed for internal consistency, construct validity, and scale dimensionality.

resultsInternal consistency for the full sample was good (α = 0.81; N = 302), with similar alphas in Cocaine (0.81; n = 177) and Cocaine/Other Stimulant (0.82; n = 92) groups, but with much lower alpha for the group without cocaine use (Other Stimulant, i.e., primarily methamphetamine, α = 0.66; n = 32). Support for construct validity was evidenced by significant positive correlations (r = 0.17 to 0.67) with measures of stimulant craving, depressive symptoms, and pain. Four factors were revealed. Conclusions/Importance: The Stimulant Selective Severity Assessment is a new measure that can be used to assess withdrawal symptoms in users of cocaine or cocaine plus methamphetamine, but it should not be administered to users of methamphetamine only.

Indexed as

CravingAdultCentral Nervous System StimulantsCocaineFemaleHumansMaleMethamphetamineMiddle AgedSeverity of Illness IndexSubstance Withdrawal SyndromeYoung AdultCentral Nervous System StimulantsCocaineMethamphetaminecocainemeasuremethamphetamineStimulantwithdrawal

Identifiers

PMID30657406
PMCPMC6438747
OpenAlexW2910733112

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.