ArticleActa bio-medica : Atenei Parmensis2019
The impact of different rheumatic diseases on health-related quality of life: a comparison with a selected sample of healthy individuals using SF-36 questionnaire, EQ-5D and SF-6D utility values.
Article in Acta bio-medica : Atenei Parmensis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05041868 (Physical Rehabilitation in Women With Scleroderma), which is not on this map. Cited by 54 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Physical Rehabilitation in Women With Scleroderma: Effects on Pulmonary Function, Lung Ultrasound, Muscle Function, Hand Functional, Functional Capacity, and Quality of Life
Who cites it
54 citing papers in PubMed, 7 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- Climatotherapy in marine and dead sea environments for musculoskeletal and rheumatologic conditions: a systematic review of effectiveness and safety.International journal of biometeorology · 2026Pooled it
- Circulating Fetuin-A concentrations in rheumatic diseases: a systematic review and meta-analysis.European journal of clinical investigation · 2025Pooled it
- Effectiveness of Ecological Momentary Interventions on Pain, Mental Health, and Quality of Life in Individuals With Rheumatic Diseases: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of nursing management · 2025Pooled it
- Health state utility values in patients with Ankylosing Spondylitis: a systematic review and meta-analysis.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Pooled it
- Mobile health technologies for the management of rheumatic diseases: a systematic review of online stores in Brazil.Clinical rheumatology · 2021Pooled it
- Pooled it
- Frailty in people with rheumatoid arthritis: a systematic review of observational studies.Wellcome open research · 2021Pooled it
- mHealth-Based Self-Management Program for Patients With Rheumatoid Arthritis: A Pilot Randomized Controlled Study.Nursing & health sciences · 2024Trial
- Impact of tanezumab on health status, non-work activities and work productivity in adults with moderate-to-severe osteoarthritis.BMC musculoskeletal disorders · 2022Trial
- Online peer support in rheumatology: a mixed methods exploration of patient and clinician views and experiences.Rheumatology (Oxford, England) · 2026Article
- An internet-based cognitive-behavioral self-management intervention for patients with hand osteoarthritis or fibromyalgia - Two randomized controlled trials.Internet interventions · 2026Article
- A Scoping Review on Artificial Intelligence-Supported Interventions for Nonpharmacologic Management of Chronic Rheumatic Diseases.Arthritis care & research · 2026Article
- Health-related quality of life among people with rheumatic and musculoskeletal diseases in Cyprus: a cross-sectional study of disease burden and time since diagnosis.BMC rheumatology · 2026Article
- Impact of clinical symptoms on quality of life in adult hypophosphatasia: a monocentric study in northern Germany.JBMR plus · 2026Article
- Comprehensiveness and validity of a multidimensional assessment of patients with fibromyalgia: a prospective cohort study.BMC musculoskeletal disorders · 2025Article
- Assessment of Health-Related Quality of Life in Patients with Active Versus Inactive Adult-Onset Still's Disease: Data from the PRO-AOSD Survey During the COVID-19 Pandemic.Journal of clinical medicine · 2025Article
- Evaluating the Divide Between Patients' and Physicians' Perceptions of Adult-Onset Still's Disease Cases: Insights from the PRO-AOSD Survey.Journal of clinical medicine · 2025Article
- Clinical Application of Infrared Thermography in Rheumatic Diseases: A Systematic Review.Mediterranean journal of rheumatology · 2025Article
- Effectiveness of tuberculosis preventive treatment in patients with rheumatic diseases: a global systematic review and meta-analysis.EClinicalMedicine · 2025Article
- Patient perspectives on rheumatic and musculoskeletal diseases: insights from a large-scale survey.Clinical rheumatology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGiven the high prevalence of rheumatic diseases, there is a need to determine which conditions have the greatest impact on health-related quality of life (HRQoL). The main aim of this study was to explore the HRQoL scores among 14 different rheumatic diseases and to compare them with the results of a selecting sample of healthy controls.
methods2633 patients of an ongoing cohort have been enrolled. Rheumatic diseases were classified into five diagnostic groups: inflammatory rheumatic diseases, connective tissue disorders, symptomatic peripheral osteoarthritis, soft tissue disorders, and osteoporosis. For comparison were used 649 healthy controls. The HRQoL was evaluated with the Medical Outcomes Study Short-Form 36 Health Survey (SF-36), the EuroQol five Dimensions (EQ-5D) questionnaire, and the Short-Form six Dimensions (SF-6D) questionnaire.
resultsThe five major rheumatic disease groups, compared to healthy people, significantly impaired all eight health concepts of the SF-36 (p <0.0001). Similar results were found for EQ-5D and SF-6D. The patients with inflammatory rheumatic diseases have poorer self-reported health status than those without arthritis in all domains of living, but particularly with respect to scales measuring aspects of physical functioning or mobility, role limitation due to physical health problems and usual activities, and bodily pain. Rheumatoid arthritis had the largest negative impact on HRQoL, followed by fibromyalgia, vertebral fractures due to osteoporosis, hip osteoarthritis, and systemic sclerosis.
conclusionsOur results indicate that rheumatic diseases have a clearly detrimental effect on the HRQoL, and physical domain is more impaired than mental and social ones.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.