Evidence map›Paper›PMID 30657107›Full record

ArticleMicrobiology spectrum2019

The Biology of

J A Lemos, S R Palmer, L Zeng, Z T Wen, J K Kajfasz, I A Freires, J Abranches, L J Brady

2 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in Microbiology spectrum, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 495 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
495citing papers in PubMed, 2 pooled it
43.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05437874 phase1completednot on this map

Effects of Carbonated Beverage Consumption on Oral pH and Bacterial Proliferation in Adolescents: A Randomized Crossover Clinical Trial.

TypeinterventionalSponsorHospital Infantil de Mexico Federico GomezRan2018 to 2019Enrolled18ConditionspH, Saliva, Dental PlaqueArmsNatural Water
NCT06575335 nacompletednot on this mapstarted 2024, after this paper: background citation

Antibacterial Efficacy of Triphala Tooth Wipes in Reduction of Streptococcus Mutans Colonies in Differently Abled Children- A Randomized Clinical Trial

TypeinterventionalSponsorDow University of Health SciencesRan2024 to 2024Enrolled60ConditionsPlaque ControlArmsTriphala Tooth Wipe, Chlorhexidine Tooth Wipe
3 · Its place in the literature

Who cites it

495 citing papers in PubMed, 2 syntheses or guidelines pooled it, 813 citations in OpenAlex.

  1. Pooled it
  2. Key virulence genes associated withFrontiers in oral health · 2025
    Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Virulence · 2026
    Article
  7. Article
  8. Article
  9. Comparison ofMicrobiology (Reading, England) · 2026
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. An XRE-type regulator inMicrobiology spectrum · 2026
    Article
  19. Article
  20. Article

435 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

J A LemosDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, FL 32610.
S R PalmerDivision of Biosciences, College of Dentistry, Ohio State University, Columbus, OH 43210.
L ZengDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, FL 32610.
Z T WenDepartment of Comprehensive Dentistry and Biomaterials and Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112.
J K KajfaszDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, FL 32610.
I A FreiresDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, FL 32610.
J AbranchesDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, FL 32610.
L J BradyDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, FL 32610.
Florida College · USLouisiana State University Health Sciences Center New Orleans · USThe Ohio State University · USUniversity of Florida · US

Funding

MEMBRANES OF THE DENTAL PATHOGEN STREPTOCOCCUS MUTANSR01DE008007 · NIDCR · UNIVERSITY OF FLORIDA · PI L. Jeannine Brady, Surabhi Mishra · 1986 to 2026
$8.6M
GENE REGULATION AND PHYSIOLOGY OF STREPTOCOCCUS MUTANSR01DE012236 · NIDCR · UNIVERSITY OF ROCHESTER · PI Lin Zeng · 1997 to 2026
$8.5M
Comprehensive Training Program in Oral BiologyT90DE021990 · NIDCR · UNIVERSITY OF FLORIDA · PI Jose A Lemos · 2011 to 2026
$8.2M
BrpA in Virulence Modulation of Streptococcus mutansR01DE019452 · NIDCR · LSU HEALTH SCIENCES CENTER · PI ZEZHANG TOM WEN, Hui Wu · 2009 to 2026
$6.3M
Intracellular Invasion by Streptococcus mutans: Significance in DiseaseR01DE022559 · NIDCR · UNIVERSITY OF ROCHESTER · PI Jacqueline Abranches, Christine M. Szymanski · 2013 to 2026
$4.8M
Role of the Spx Regulator in Streptococcus mutansR01DE019783 · NIDCR · UNIVERSITY OF ROCHESTER · PI LEMOS, JOSE A · 2010 to 2020
$3.7M
Functional Amyloid Formation in Streptococcus mutansR01DE021789 · NIDCR · UNIVERSITY OF FLORIDA · PI BRADY, L. JEANNINE, LONG, JOANNA R · 2012 to 2021
$3.7M
Functional amyloid formation in streptococcus mutansR56DE021789 · NIDCR · UNIVERSITY OF FLORIDA · PI BRADY, L. JEANNINE, LONG, JOANNA R · 2024 to 2024
$506k
eDNA Secretion and eDNA-Cell Interactions in Biofilm FormationR21DE025348 · NIDCR · LSU HEALTH SCIENCES CENTER · PI BRADY, L. JEANNINE, WEN, ZEZHANG TOM · 2016 to 2017
$419k
Roles of Streptococcus mutans YidC1 and YidC2 in membrane biogenesisF31DE019605 · NIDCR · UNIVERSITY OF FLORIDA · PI PALMER, SARA MARIE RASER · 2008 to 2010
$90k
Studies of YlxM of Streptococcus mutans, a newly identified component of the SignF31DE023710 · NIDCR · UNIVERSITY OF FLORIDA · PI WILLIAMS, MATTHEW LAWRENCE · 2013 to 2014
$79k
NIDCR NIH HHS F31 DE019605NIDCR NIH HHS F31 DE023710NIDCR NIH HHS R01 DE008007NIDCR NIH HHS R01 DE012236NIDCR NIH HHS R01 DE019452NIDCR NIH HHS R01 DE019783NIDCR NIH HHS R01 DE021789NIDCR NIH HHS R01 DE022559NIDCR NIH HHS R21 DE025348NIDCR NIH HHS R56 DE021789NIDCR NIH HHS T90 DE021990
6 · The paper itself

Abstract

As a major etiological agent of human dental caries,

Indexed as

BiofilmsCarbohydrate MetabolismDental CariesDental PlaqueHumansSignal TransductionStreptococcus mutans

Identifiers

PMID30657107
PMCPMC6615571
OpenAlexW2910428070

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.