Evidence map›Paper›PMID 30656738›Full record

ArticleMagnetic resonance in medicine2019

Improved repeatability of dynamic contrast-enhanced MRI using the complex MRI signal to derive arterial input functions: a test-retest study in prostate cancer patients.

Edzo M E Klawer, Petra J van Houdt, Frank F J Simonis, Cornelis A T van den Berg, Floris J Pos, Stijn W T P J Heijmink, Sofie Isebaert, Karin Haustermans, Uulke A van der Heide

Erratum issuedOpen access · hybridAbstract readMulticenter Study
In one paragraph

Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Edzo M E KlawerDepartment of Radiation Oncology, the Netherlands Cancer Institute, Amsterdam, The Netherlands.ORCID 0000-0001-9882-2149
Petra J van HoudtDepartment of Radiation Oncology, the Netherlands Cancer Institute, Amsterdam, The Netherlands.ORCID 0000-0001-7431-8386
Frank F J SimonisDepartment of Radiation Oncology, Imaging Division, University Medical Center, Utrecht, The Netherlands.ORCID 0000-0002-0734-1778
Cornelis A T van den BergDepartment of Radiation Oncology, Imaging Division, University Medical Center, Utrecht, The Netherlands.ORCID 0000-0002-5565-6889
Floris J PosDepartment of Radiation Oncology, the Netherlands Cancer Institute, Amsterdam, The Netherlands.
Stijn W T P J HeijminkDepartment of Radiology, the Netherlands Cancer Institute, Amsterdam, The Netherlands.
Sofie IsebaertDepartment of Radiation Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium.
Karin HaustermansDepartment of Radiation Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium.
Uulke A van der HeideDepartment of Radiation Oncology, the Netherlands Cancer Institute, Amsterdam, The Netherlands.ORCID 0000-0002-4146-6419
The Netherlands Cancer Institute · NLKU Leuven · BEUtrecht University · NLDutch Cancer Society · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe arterial input function (AIF) is a major source of uncertainty in tracer kinetic (TK) analysis of dynamic contrast-enhanced (DCE)-MRI data. The aim of this study was to investigate the repeatability of AIFs extracted from the complex signal and of the resulting TK parameters in prostate cancer patients.

methodsTwenty-two patients with biopsy-proven prostate cancer underwent a 3T MRI exam twice. DCE-MRI data were acquired with a 3D spoiled gradient echo sequence. AIFs were extracted from the magnitude of the signal (AIF

resultsThe wCV for peak height and full width at half maximum for AIF

conclusionRepeatability of AIF

Indexed as

Magnetic Resonance ImagingAgedAlgorithmsBiopsyComputer SimulationContrast MediaHumansImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedKineticsMaleMiddle AgedModels, StatisticalProstatic NeoplasmsReproducibility of ResultsContrast Mediaarterial input functioncomplex signaldynamic contrast-enhanced MRIprostate cancerrepeatabilitytracer kinetic analysis

Identifiers

PMID30656738
PMCPMC6590420
OpenAlexW2909586571

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.