Evidence map›Paper›PMID 30656708›Full record

ArticleAllergy2019

Association of type 2 cytokines in severe rhinovirus bronchiolitis during infancy with risk of developing asthma: A multicenter prospective study.

Kohei Hasegawa, Claire E Hoptay, Brennan Harmon, Juan C Celedón, Jonathan M Mansbach, Pedro A Piedra, Robert J Freishtat, Carlos A Camargo

Open access · greenAbstract readLetterMulticenter Study
In one paragraph

Article in Allergy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

  1. Viral and Host-Related Factors in the Nasal Inflammatory Response to Critical Bronchiolitis in Infants and Children.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2026
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  14. Integrated associations of nasopharyngeal and serum metabolome with bronchiolitis severity and asthma: A multicenter prospective cohort study.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2021
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  17. Respiratory viruses are associated with serum metabolome among infants hospitalized for bronchiolitis: A multicenter study.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Kohei HasegawaDepartment of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0002-5739-7999
Claire E HoptayCenter for Genetic Medicine Research, Children's National Health System, Washington, District of Columbia.
Brennan HarmonCenter for Genetic Medicine Research, Children's National Health System, Washington, District of Columbia.
Juan C CeledónDivision of Pulmonary Medicine, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania.ORCID 0000-0002-6139-5320
Jonathan M MansbachDepartment of Pediatrics, Boston Children's Hospital, Boston, Massachusetts.
Pedro A PiedraDepartment of Molecular Virology and Microbiology and Pediatrics, Baylor College of Medicine, Houston, Texas.
Robert J FreishtatCenter for Genetic Medicine Research, Children's National Health System, Washington, District of Columbia.
Carlos A CamargoDepartment of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Children's National · USHarvard University · USBaylor College of Medicine · USBoston Children's Hospital · USUniversity of Pittsburgh · US

Funding

Host genetics, early-life microbiome, and childhood asthma: MARC-43 BostonUH3OD023253 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CARLOS ARTURO CAMARGO · 2018 to 2026
$12.1M
Nasal microRNA during bronchiolitis and age 6y asthma phenotypes: MARC-35 cohortR01AI127507 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CAMARGO, CARLOS ARTURO, FREISHTAT, ROBERT J · 2017 to 2021
$8.0M
Host genetics, early-life microbiome, and childhood asthma: MARC-43 BostonUG3OD023253 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CAMARGO, CARLOS ARTURO · 2016 to 2024
$6.8M
Prospective Cohort Study of Severe Bronchiolitis and Risk of Recurrent WheezingU01AI087881 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CAMARGO, CARLOS ARTURO · 2011 to 2016
$6.2M
Airway dual-transcriptomics in bronchiolitis and risk of asthma: MARC-35 cohortR01AI137091 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HASEGAWA, KOHEI · 2018 to 2022
$4.3M
Infant specific-IgE, rhinovirus-C bronchiolitis, and incident asthma in MARC-35R01AI114552 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CAMARGO, CARLOS ARTURO · 2015 to 2019
$4.2M
Airway metagenome & metabolome in bronchiolitis and risk of asthma: MARC-35 cohortR01AI134940 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HASEGAWA, KOHEI · 2018 to 2022
$4.0M
Cytokines & transcriptomes in rhinovirus bronchiolitis and risk of incident asthmaR21HL129909 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI HASEGAWA, KOHEI · 2015 to 2016
$506k
Prospective Study of Diet, Physical Activity, BMI and Risk of Pulmonary EmbolismR21AG031079 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI CAMARGO, CARLOS ARTURO · 2007 to 2008
$429k
NHLBI NIH HHS R21 HL129909NIAID NIH HHS R01 AI114552NIAID NIH HHS R01 AI127507NIAID NIH HHS R01 AI134940NIAID NIH HHS R01 AI137091NIAID NIH HHS U01 AI087881NIA NIH HHS R21 AG031079NIH HHS UG3 OD023253NIH HHS UH3 OD023253
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AsthmaBiomarkersBronchiolitis, ViralChildChild, PreschoolCytokinesDisease SusceptibilityFemaleHumansInfantMalePicornaviridae InfectionsRhinovirusBiomarkersCytokinesairwayasthmabronchiolitiscytokinesinfants

Identifiers

PMID30656708
PMCPMC6640081
OpenAlexW2910786449

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.