ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2019
Sonication of removed implants improves microbiological diagnosis of postoperative spinal infections.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 36 citations in OpenAlex.
- Assessment of Sonication for Diagnosing Implant-Associated Infections in Spinal Surgery Routine Practice.Microorganisms · 2025Article
- Mid- to Long-Term Outcomes of Two-Stage Revision Arthroplasty for Periprosthetic Joint Infection of the Shoulder.Journal of clinical medicine · 2025Article
- The identification of low-pathogenic bacteria on removed spinal implants and implications for antimicrobial prophylaxis.Brain & spine · 2025Article
- Practical Guidance for Clinical Microbiology Laboratories: Microbiologic diagnosis of implant-associated infections.Clinical microbiology reviews · 2024Review
- Global Trends in Orthopedic Biofilm Research: A Bibliometric Analysis of 1994-2022.Journal of multidisciplinary healthcare · 2024Article
- Comparison of Mid-Infrared Handheld and Benchtop Spectrometers to DetectBioengineering (Basel, Switzerland) · 2023Article
- Tissue sampling is non-inferior in comparison to sonication in orthopedic revision surgery.Archives of orthopaedic and trauma surgery · 2023Article
- A prospective study to identify preoperative serum parameters for spinal implant infection detected by sonication fluid culture.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2023Article
- Review
- Manual Homogenization Improves the Sensitivity of Microbiological Culture for Patients with Pyogenic Spondylitis.Infection and drug resistance · 2022Article
- Clinical presentation and diagnosis of acute postoperative spinal implant infection (PSII).Journal of spine surgery (Hong Kong) · 2020Review
- Implications for diagnosis and treatment of peri-spinal implant infections from experiences in periprosthetic joint infections-a literature comparison and review.Journal of spine surgery (Hong Kong) · 2020Review
- Comprehensive treatment algorithm of postoperative spinal implant infection.Journal of spine surgery (Hong Kong) · 2020Review
- Surgical revision strategies for postoperative spinal implant infections (PSII).Journal of spine surgery (Hong Kong) · 2020Review
- Antibiotic treatment of postoperative spinal implant infections.Journal of spine surgery (Hong Kong) · 2020Review
- Clinical presentation and diagnosis of delayed postoperative spinal implant infection.Journal of spine surgery (Hong Kong) · 2020Article
- [Evidence-based implant choice in infections of the spine : Is it a gut thing, after all?]Der Orthopade · 2020Review
- The Michel Benoist and Robert Mulholland yearly European spine journal review: a survey of the "surgical and research" articles in European spine journal, 2019.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2020Review
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIn total joint replacement, culturing of the sonication fluid of removed implants has proven to be more sensitive than conventional periprosthetic tissue culture for the microbiological diagnosis of prosthetic joint infection. However, its role in postoperative spinal implant infection (PSII) is not well investigated. Therefore, the aim of this study was to determine the validity of sonication in detecting infection following instrumented spine surgery.
methodsIn this prospective controlled consecutive cohort study, patients undergoing spinal revision between September 2016 and March 2018 were analyzed. In all patients sonication of removed spinal implants and at least one peri-implant tissue culture were performed. Demographic data, including age, gender, clinical manifestation, comorbidities, laboratory values (CRP and blood leukocytes), were recorded. Microorganisms causing PSII were documented. Sensitivity and specificity of sonication and peri-implant tissue culture were evaluated.
resultsA total of 118 patients were included. PSII was diagnosed in 35 patients, representing 29.6% of the study cohort. Sensitivities of tissue and sonication fluid culture were 65.7% (95% confidence interval (CI) 48.6-80.0) and 94.3% (95% CI 85.7-100) (p value = 0.002) and specificities 96.4% (95% CI 91.6-100) and 98.8% (95% CI 96.4-100), respectively. The most common microorganisms found in PSII were coagulase-negative Staphylococci and Propionibacterium acnes. Eleven PSIIs were detected only by sonicate fluid culture.
conclusionsCulture of samples obtained by spinal implant sonication was more sensitive than conventional peri-implant tissue culture for the microbiological diagnosis of PSII. Therefore, sonication should be used as a routine tool in the diagnostic workup of PSII. These slides can be retrieved under Electronic Supplementary Material.
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