Evidence map›Paper›PMID 30656364›Full record

ReviewPsychopharmacology2019

Neurochemical and molecular mechanisms underlying the retrieval-extinction effect.

Emma N Cahill, Amy L Milton

Abstract readReview
In one paragraph

Review in Psychopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Reconsolidation and Fear Extinction: An Update.Current topics in behavioral neurosciences · 2023
    Article
  11. Review
  12. Review
  13. Review
  14. Neural Computations of Threat.Trends in cognitive sciences · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. The role of carbonic anhydrases in extinction of contextual fear memory.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Emma N CahillDepartment of Physiology, Development and Neuroscience, University of Cambridge, Downing Site, Cambridge, CB2 3EG, UK.
Amy L MiltonDepartment of Psychology, University of Cambridge, Downing Site, Cambridge, CB2 3EB, UK. alm46@cam.ac.uk.ORCID http://orcid.org/0000-0003-0175-9417

Funding

Biotechnology and Biological Sciences Research Council BB/M01407X/1Medical Research Council MR/N02530X/1
6 · The paper itself

Abstract

Extinction within the reconsolidation window, or 'retrieval-extinction', has received much research interest as a possible technique for targeting the reconsolidation of maladaptive memories with a behavioural intervention. However, it remains to be determined whether the retrieval-extinction effect-a long-term reduction in fear behaviour, which appears resistant to spontaneous recovery, renewal and reinstatement-depends specifically on destabilisation of the original memory (the 'reconsolidation-update' account) or represents facilitation of an extinction memory (the 'extinction-facilitation' account). We propose that comparing the neurotransmitter systems, receptors and intracellular signalling pathways recruited by reconsolidation, extinction and retrieval-extinction will provide a way of distinguishing between these accounts.

Indexed as

AnimalsConditioning, PsychologicalExtinction, PsychologicalFearHumansMemoryReceptors, DopamineReceptors, N-Methyl-D-AspartateReceptors, DopamineReceptors, N-Methyl-D-AspartateBehaviourExtinctionMemoryReconsolidationRetrieval-Extinction

Identifiers

PMID30656364
PMCPMC6373198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.