Evidence map›Paper›PMID 30656171›Full record

ArticleJournal of exercise rehabilitation2018

The effectiveness of gabapentin and exercises in the treatment of carpal tunnel syndrome: a randomized clinical trial.

Omid Hesami, Mahsa Haghighatzadeh, Behnam Safarpour Lima, Naghmeh Emadi, Shahin Salehi

3 registry-linked trialsOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of exercise rehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04025203 phase4completednot on this mapstarted 2019, after this paper: background citation

Pain Reduction and Changes in Upper Limb Function Produced by Physiotherapy, Ibuprofen Arginine, Gabapentin and the Absence of Treatment, in Carpal Tunnel Syndrome

TypeinterventionalSponsorFrancisco Unda SolanoRan2019 to 2019Enrolled196ConditionsCarpal Tunnel SyndromeArmsMedian nerve neural mobilization, Ibuprofen Arginine, Gabapentin
NCT04285281 phase4completednot on this mapstarted 2020, after this paper: background citation

Oral Gabapentin and Median Nerve Neural Mobilization Versus Control in the Treatment of Carpal Tunnel Syndrome

TypeinterventionalSponsorUniversidad Europea de MadridRan2020 to 2020Enrolled126ConditionsCarpal Tunnel SyndromeArmsGabapentin oral capsules, Median nerve neural mobilization
NCT04329247 nacompletednot on this mapstarted 2020, after this paper: background citation

Physical Therapy Versus Control in the Treatment of Carpal Tunnel Syndrome

TypeinterventionalSponsorUniversidad Europea de MadridRan2020 to 2020Enrolled74ConditionsCarpal Tunnel SyndromeArmsMedian nerve neural mobilization
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Omid HesamiDepartment of Neurology, Imam Hossein Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran.
Mahsa HaghighatzadehDepartment of Neurology, Imam Hossein Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran.
Behnam Safarpour LimaDepartment of Neurology, Imam Hossein Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran.
Naghmeh EmadiDentofacial Deformities Research Center, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Shahin SalehiDepartment of Sports Medicine, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-2874-0436
Imam Hossein Hospital · IRShahid Beheshti University of Medical Sciences · IRShahid Beheshti University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carpal tunnel syndrome (CTS) is one of the reasons for labor abandonment due to inability and pain. The aim of this study was to evaluate the effectiveness of gabapentin and exercise training in the treatment of CTS and compare their effects. This single-blind clinical trial was conducted on patients referred to the Imam Hossein hospital's electrodiagnostic (EDX) unit. The patients randomly assigned into four groups: using nocturnal splint as an approved treatment in the control group; taking 300-mg gabapentin per night and using nocturnal splint; nerve and tendon gliding exercises and using nocturnal splint; and taking 300-mg gabapentin per night, performing same exercise as group 3 and using nocturnal splint. At baseline, four indicators were assessed in all patients, including the Boston carpal tunnel questionnaire, visual analogue scale (VAS), pinch and grip strength of the affected hand. One month after the beginning of intervention, participants were reassessed and compared for each of the four indicators. Using nocturnal splint along with exercise and gabapentin significantly improved VAS, pinch and grip strength in moderate CTS compared to control group that only used nocturnal splint. However in mild CTS, grip strength was not significantly higher compared to control group (

Indexed as

Boston carpal tunnel questionnaireCarpal tunnel syndromeExerciseGabapentinGrip and pinch strengthVisual analogue scale

Identifiers

PMID30656171
PMCPMC6323333
OpenAlexW2906863571

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.