ArticlePeerJ2019
Global genomic similarity and core genome sequence diversity of the
Article in PeerJ, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- The methanogen core and pangenome: conservation and variability across biology's growth temperature extremes.DNA research : an international journal for rapid publication of reports on genes and genomes · 2023Article
- StreptococcusMicrobiology spectrum · 2022Article
- Antifungal Activity and Biosynthetic Potential of NewInternational journal of molecular sciences · 2021Article
- The Thermosynechococcus Genus: Wide Environmental Distribution, but a Highly Conserved Genomic Core.Microbes and environments · 2021Article
- A review of Listeria monocytogenes from meat and meat products: Epidemiology, virulence factors, antimicrobial resistance and diagnosis.The Onderstepoort journal of veterinary research · 2020Review
- Whole-Genome Sequencing of Bacterial Isolates That Degrade the Cyanobacterial Toxin Microcystin-LR.Microbiology resource announcements · 2020Article
- Single Core Genome Sequencing for Detection of bothInternational journal of environmental research and public health · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe
methodsCore and pan-genomes described the genomic diversity of 108 strains belonging to 16
resultsThe core genome, in this work, consists of 404 proteins that are shared by all 108 DISCUSSION: Understanding of genomic variability and species relatedness is the goal of tools like GSS, which makes use of the maximum pairwise shared orthologous sequences for its calculation. It allows for long evolutionary distances (above species) to be included because of the use of amino acid alignment scores, rather than nucleotides, and normalizing by positive matches. Newly sequenced species and strains could be easily placed into GSS dendrograms to infer overall genomic relatedness. The GSS is not restricted to ubiquitous conservancy of gene features; thus, it reflects the mosaic-structure and dynamism of gene acquisition and loss in bacterial genomes.
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Registered trials
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