Evidence map›Paper›PMID 30656036›Full record

ArticleClinical case reports2019

Abdominal pain in combination with an unexplained hemolytic anemia are crucial signs to test for paroxysmal nocturnal hemoglobinuria: A case report.

N S Elias, Jürgen Riedl, Karlijn Stouten, Mark-David Levin, Frank Wolfhagen, Mathijs Eefting, Henricus Jan Vermeer

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

N S EliasDepartment of Clinical Chemistry Albert Schweitzer Hospital Dordrecht The Netherlands.ORCID 0000-0001-7086-7564
Jürgen RiedlDepartment of Clinical Chemistry Albert Schweitzer Hospital Dordrecht The Netherlands.
Karlijn StoutenDepartment of Clinical Chemistry Albert Schweitzer Hospital Dordrecht The Netherlands.
Mark-David LevinDepartment of Internal Medicine Albert Schweitzer Hospital Dordrecht The Netherlands.
Frank WolfhagenDepartment of Internal Medicine Albert Schweitzer Hospital Dordrecht The Netherlands.
Mathijs EeftingDepartment of Hematology Beatrix Hospital Gorinchem The Netherlands.
Henricus Jan VermeerDepartment of Clinical Chemistry Albert Schweitzer Hospital Dordrecht The Netherlands.
Albert Schweitzer Ziekenhuis · NLBeatrix Kinderziekenhuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paroxysmal nocturnal hemoglobinuria (PNH), a rare benign hematological disorder, presents with a wide variety of clinical symptoms. A direct Coombs-negative hemolytic anemia combined with an increased LDH = Lactate dehydrogenase level are signs to test for PNH. Follow-up does not need any microscopic review's only flow cytometric PNH clone size.

Indexed as

abdominal painCoombs‐negative hemolysisflow cytometryhemolytic anemiaParoxysmal nocturnal hemoglobinuria

Identifiers

PMID30656036
PMCPMC6333074
OpenAlexW2903457849

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.