Evidence map›Paper›PMID 30655961›Full record

ArticleACS medicinal chemistry letters2019

Synthesis, Profiling, and in Vivo Evaluation of Cyclopeptides Containing

Catherine Fagundez, Diver Sellanes, Stella Peña, Laura Scarone, Anna C C Aguiar, Juliana O de Souza, Rafael V C Guido, Lindsay Stewart, Vanessa Yardley, Sabine Ottilie and 4 more

Abstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Synthesis and antiplasmodial assessment of nitazoxanide and analogs as new antimalarial candidates.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2022
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Catherine FagundezLaboratorio de Química Farmacéutica (DQO), Facultad de Química, Universidad de la República, Gral. Flores 2124, Montevideo, CP 11800, Uruguay.
Diver SellanesLaboratorio de Química Farmacéutica (DQO), Facultad de Química, Universidad de la República, Gral. Flores 2124, Montevideo, CP 11800, Uruguay.
Stella PeñaLaboratorio de Química Farmacéutica (DQO), Facultad de Química, Universidad de la República, Gral. Flores 2124, Montevideo, CP 11800, Uruguay.
Laura ScaroneLaboratorio de Química Farmacéutica (DQO), Facultad de Química, Universidad de la República, Gral. Flores 2124, Montevideo, CP 11800, Uruguay.
Anna C C AguiarInstituto de Física de São Carlos, Universidade de São Paulo, São Paulo, Brazil.
Juliana O de SouzaInstituto de Física de São Carlos, Universidade de São Paulo, São Paulo, Brazil.
Rafael V C GuidoInstituto de Física de São Carlos, Universidade de São Paulo, São Paulo, Brazil.
Lindsay StewartFaculty of Infectious & Tropical Disease, The London School of Hygiene & Tropical Medicine (LSHTM), Keppel Street, London, WC1E 7HT, U.K.
Vanessa YardleyFaculty of Infectious & Tropical Disease, The London School of Hygiene & Tropical Medicine (LSHTM), Keppel Street, London, WC1E 7HT, U.K.
Sabine OttilieSchool of Medicine, University of California San Diego, La Jolla, California 92093, United States.
Elizabeth A WinzelerSchool of Medicine, University of California San Diego, La Jolla, California 92093, United States.
Francisco-J GamoDiseases of the Developing World (DDW), Tres Cantos Medicines Development Campus, GlaxoSmithKline, Tres Cantos, Spain.
Laura M SanzDiseases of the Developing World (DDW), Tres Cantos Medicines Development Campus, GlaxoSmithKline, Tres Cantos, Spain.
Gloria L SerraLaboratorio de Química Farmacéutica (DQO), Facultad de Química, Universidad de la República, Gral. Flores 2124, Montevideo, CP 11800, Uruguay.

Funding

Experimental Annotation of the P. Falciparum GenomeR01AI059472 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI WINZELER, ELIZABETH A · 2005 to 2009
$2.2M
NIAID NIH HHS R01 AI059472
6 · The paper itself

Abstract

Malaria is a major tropical disease where important needs are to mitigate symptoms and to prevent the establishment of infection. Cyclopeptides containing

Identifiers

PMID30655961
PMCPMC6331169

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.