ArticleReproductive medicine and biology2019
Effect of
Article in Reproductive medicine and biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Maca (Frontiers in pharmacology · 2022Pooled it
- Effects of oral black Maca (The veterinary quarterly · 2025Article
- Therapeutic effect ofRSC advances · 2025Article
- Effects of Different Diluents and Freezing Methods on Cryopreservation of Hu Ram Semen.Veterinary sciences · 2024Article
- Effect of Maca aqueous extract addition to a freezing extender for canine semen.Veterinary research communications · 2024Article
- Improving fertilization rates in IVF using rutin and quercetin in preculture medium or through oral administration.Frontiers in veterinary science · 2024Article
- Influence of dietary supplementation withFrontiers in veterinary science · 2024Article
- Effect of Atomized Black Maca (Animals : an open access journal from MDPI · 2023Article
- Extraction of polysaccharides from Maca enhances the treatment effect of 5-FU by regulating CD4Heliyon · 2023Article
- Exceptional Properties ofMolecules (Basel, Switzerland) · 2022Article
- Effect of Aqueous Extract of Maca Addition to an Extender for Chilled Canine Semen.Animals : an open access journal from MDPI · 2022Article
- First study ofVeterinary world · 2022Article
- Complementary effects of coenzyme Q10 andInternational journal of reproductive biomedicine · 2021Article
- Fertilization with human sperm bound to zona pellucida by pressing onto the oocyte membrane.Human cell · 2020Article
- Effect ofReproductive medicine and biology · 2019Article
- In vitro fertilization using sperm activated by ML-2-3 isolated fromReproductive medicine and biologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe direct effects of
methodsWe examined the fertilization rate in a mouse model and the rate of acrosome reaction in sperm from transgenic mice expressing enhanced green fluorescent protein (EGFP) in a Maca extract-containing human tubal fluid (HTF) medium. Using human sperm, we assessed acrosome status via fluorescein isothiocyanate-conjugated peanut agglutinin (FITC-PNA) staining and performed detailed analysis using a sperm motility analysis system (SMAS).
resultsIn the mouse model, the fertilization rate in the Maca extract-containing HTF was significantly higher than that in the control medium. The acrosome reaction rate in sperm from transgenic mice expressing EGFP was also significantly higher in the Maca extract-containing HTF than that in the control medium. Similarly, a high acrosome reaction rate, identified via FITC-PNA staining of human sperm samples, was found in the Maca extract-containing HTF compared with that in the control medium. Human sperm motility in the Maca extract-containing HTF was also increased compared with that in the control medium as measured using an SMAS.
conclusionsMaca improved in vitro fertilization rates by inducing an acrosome reaction and increasing sperm motility.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.