Evidence map›Paper›PMID 30655662›Full record

SynthesisClinical interventions in aging2019

Tai chi for treating osteopenia and primary osteoporosis: a meta-analysis and trial sequential analysis.

Yili Zhang, Yan Chai, Xiaojie Pan, Hao Shen, Xu Wei, Yanming Xie

Open access · goldAbstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Clinical interventions in aging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 6 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 6 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Consequences of Aging on Bone.Aging and disease · 2023
    Pooled it
  3. Efficacy and safety of tai chi exercise on bone health: An umbrella review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Mind-Body Exercise for Anxiety and Depression in COPD Patients: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2019
    Pooled it
  7. Trial
  8. Review
  9. Article
  10. The impact of Tai Chi on osteoporosis and osteopenia in middle-aged and elderly adults: a systematic review and meta-analysis of randomized controlled trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Association of Hydrogen Sulfide with Femoral Bone Mineral Density in Osteoporosis Patients: A Preliminary Study.Medical science monitor : international medical journal of experimental and clinical research · 2021
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Yili ZhangInstitute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China, datamining5288@163.com.
Yan ChaiDepartment of Epidemiology, University of California, Los Angeles, CA, USA.
Xiaojie PanDepartment of Human Nutrition and Health, Wageningen University and Health, Wageningen, The Netherlands.
Hao ShenInstitute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China, datamining5288@163.com.
Xu WeiDepartment of Scientific Research, Wangjing Hospital, China Academy of Chinese Medical Sciences, Beijing, China, weixu.007@163.com.
Yanming XieInstitute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing, China, datamining5288@163.com.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNUniversity of California, Los Angeles · USWageningen University & Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this meta-analysis was to evaluate the efficacy of Tai chi (TC) as an adjuvant treatment for osteopenia and primary osteoporosis.

methodsWe went through eight databases to identify relevant randomized controlled trials that compared TC with a control group. The primary outcome was osteoporosis-related fractures (fracture incidence). Meta-analyses and trial sequential analyses (TSA) were conducted using RevMan 5.3 and TSA 0.9.

resultsFifteen randomized controlled trials involving a total of 857 patients were included in the analyses. No trials reported primary outcome; however, bone mineral density (BMD) values differed significantly in subgroup 1 (TC vs no treatment; weighted mean difference [WMD] =0.05 g/cm

conclusionAlthough there is no study monitoring fracture incidence, TC may be beneficial for patients in improving BMD values, level of bone gla protein, and relieving osteoporotic pain. However, due to the low methodological quality, current evidence for treating osteopenia and primary osteoporosis through TC is insufficient.

Indexed as

Tai JiAgedBone DensityFemaleHumansMaleMiddle AgedOsteoporosisQuality of Lifeevidence based medicineosteopeniaprimary osteoporosisTai chitrial sequential analyses

Identifiers

PMID30655662
PMCPMC6322510
OpenAlexW2907361425

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.