Evidence map›Paper›PMID 30655570›Full record

ArticleScientific reports2019

Predictors of objective cognitive impairment and subjective cognitive complaints in patients with Fabry disease.

Simon Körver, Gert J Geurtsen, Carla E M Hollak, Ivo N van Schaik, Maria G F Longo, Marjana R Lima, Leonardo Vedolin, Marcel G W Dijkgraaf, Mirjam Langeveld

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Review
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  6. Review
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  8. Article
  9. Mechanisms of cognitive dysfunction in CKD.Nature reviews. Nephrology · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Simon KörverDepartment of Endocrinology and Metabolism, Amsterdam University Medical Centers location Academic Medical Center, Amsterdam, The Netherlands.ORCID 0000-0003-1432-7760
Gert J GeurtsenDepartment of Medical Psychology, Amsterdam University Medical Centers location Academic Medical Center, Amsterdam, The Netherlands.
Carla E M HollakDepartment of Endocrinology and Metabolism, Amsterdam University Medical Centers location Academic Medical Center, Amsterdam, The Netherlands.
Ivo N van SchaikDepartment of Neurology, Amsterdam University Medical Centers location Academic Medical Center, Amsterdam, The Netherlands.
Maria G F LongoDepartment of Radiology, Massachusetts General Hospital, Boston, United States.ORCID 0000-0001-6819-4890
Marjana R LimaDepartment of Radiology, Hospital Moinhos de Vento, Porto Alegre, Brazil.
Leonardo VedolinImaging Section, DASA, São Paulo, Brazil.
Marcel G W DijkgraafClinical Research Unit/Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam University Medical Centers location Academic Medical Center, Amsterdam, The Netherlands.
Mirjam LangeveldDepartment of Endocrinology and Metabolism, Amsterdam University Medical Centers location Academic Medical Center, Amsterdam, The Netherlands. m.langeveld@amc.uva.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the relationship between objective cognitive impairment (OCI), subjective cognitive complaints and depressive symptoms in men and women with classical and non-classical Fabry disease (FD). Cognitive functioning was assessed using a neuropsychological test battery, subjective cognitive complaints using a structured interview and depressive symptoms using a depression scale (CESD). Eighty-one patients were included (mean age 44.5 ± 14.3, 35% men, 74% classical). Subjective cognitive complaints were reported by 64% of all patients. OCI was present in thirteen patients (16%), predominantly in men with classical FD. Thirty-one patients (38%) had a high score (≥16) on the CESD scale. Male sex (OR, 6.8; 95%CI, 1.6-39.8; p = 1.6 * 10

Indexed as

AdultCognition DisordersCognitive DysfunctionDepressive DisorderFabry DiseaseFemaleHumansInterview, PsychologicalMaleMiddle AgedNeuropsychological TestsSex FactorsStroke

Identifiers

PMID30655570
PMCPMC6336934

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.